Glutamate is the major excitatory neurotransmitter in the central nervous system. Glutamate
transmission efficiency depends on the correct functionality and expression of a plethora of …

After more than 100 years of research, the neuropathology of schizophrenia remains
unknown and this is despite the fact that both: Kraepelin, E., 1919/1971. Dementia praecox …

Recent studies suggest that excitatory amino acids (EAAs) have a wide variety of
physiological and pathophysiological roles during central nervous system (CNS) …

Extracellular concentrations of the predominant excitatory neurotransmitter, glutamate, and
related excitatory amino acids are maintained at relatively low levels to ensure an …

Schizophrenia is a syndrome, undoubtedly with multiple etiologies, that variably exhibits
several features including positive and negative symptoms, cognitive deficits, onset in young …

The structure and function of the chemicals contributing to the three main peaks seen with
1H NMR spectroscopy, N‐acetyl‐L‐aspartate (NAA), creatine/phosphocreatine (Cr), and …

The recent discovery of glycine transporters in both the central nervous system and the
periphery suggests that glycine transport may be critical to N-methyl-d-aspartate receptor …

• The intravitreal injection of steroids may be potentially useful in the treatment of
endophthalmitis and other ocular inflammatory diseases. The retinal toxicity and intraocular …

Using the N18‐RE‐105 neuroblastoma X retina cell line, we previously described Ca2+‐
dependent quisqualate‐type glutamate toxicity caused by the inhibition of high‐affinity …

Background: Schizophrenia has been hypothesized to be caused by a hypofunction of
glutamatergic neurons. Findings of reduced concentrations of glutamate in the cerebrospinal …