Cells of the human intestinal tract mapped across space and time
The cellular landscape of the human intestinal tract is dynamic throughout life, develo** in
utero and changing in response to functional requirements and environmental exposures …
utero and changing in response to functional requirements and environmental exposures …
Biomaterial-guided stem cell organoid engineering for modeling development and diseases
Organoids are miniature models of organs to recapitulate spatiotemporal cellular
organization and tissue functionality. The production of organoids has revolutionized the …
organization and tissue functionality. The production of organoids has revolutionized the …
Mesenchymal niches for digestive organ development, homeostasis, and disease
Mesenchymal–epithelial crosstalk plays a crucial role in organ development and stem cell
function. However, the identity of the mesenchymal cells involved in this exchange was …
function. However, the identity of the mesenchymal cells involved in this exchange was …
[HTML][HTML] R-SPONDIN2+ mesenchymal cells form the bud tip progenitor niche during human lung development
The human respiratory epithelium is derived from a progenitor cell in the distal buds of the
develo** lung. These" bud tip progenitors" are regulated by reciprocal signaling with …
develo** lung. These" bud tip progenitors" are regulated by reciprocal signaling with …
Chromatin regulatory dynamics of early human small intestinal development using a directed differentiation model
The establishment of the small intestinal (SI) lineage during human embryogenesis ensures
functional integrity of the intestine after birth. The chromatin dynamics that drive SI lineage …
functional integrity of the intestine after birth. The chromatin dynamics that drive SI lineage …
Distinct airway progenitor cells drive epithelial heterogeneity in the develo** human lung
Recent advances using single cell genomic approaches have identified new epithelial cell
types and uncovered cellular heterogeneity in the murine and human lung. Here, using …
types and uncovered cellular heterogeneity in the murine and human lung. Here, using …
Science shines in a new virtual SY-Stem
The third 'Symposium for the Next Generation of Stem Cell Research'(SY-Stem) was held
virtually on 3-5 March 2021, having been cancelled in 2020 due to the COVID-19 pandemic …
virtually on 3-5 March 2021, having been cancelled in 2020 due to the COVID-19 pandemic …