The Helicobacter pylori cag pathogenicity island as a determinant of gastric cancer risk

SC Tran, KN Bryant, TL Cover - Gut Microbes, 2024 - Taylor & Francis
Helicobacter pylori strains can be broadly classified into two groups based on whether they
contain or lack a chromosomal region known as the cag pathogenicity island (cag PAI) …

Novel carbonic anhydrase inhibitors for the treatment of Helicobacter pylori infection

CT Supuran - Expert Opinion on Investigational Drugs, 2024 - Taylor & Francis
Introduction Helicobacter pylori, the causative agent of peptic ulcer, gastritis, and gastric
cancer encodes two carbonic anhydrases (CA, EC 4.2. 1.1) belonging to the α-and β-class …

40 years after the discovery of Helicobacter pylori: towards elimination of H pylori for gastric cancer prevention

JM Liou, P Malfertheiner, SI Smith, EM El-Omar, MS Wu - The Lancet, 2024 - thelancet.com
The discovery of Helicobacter pylori 40 years ago revolutionised the prevention and
treatment of gastritis, peptic ulcers, and gastric cancer, earning Barry Marshall and Robin …

An ancient ecospecies of Helicobacter pylori

E Tourrette, RC Torres, SL Svensson, T Matsumoto… - Nature, 2024 - nature.com
Helicobacter pylori disturbs the stomach lining during long-term colonization of its human
host, with sequelae including ulcers and gastric cancer,. Numerous H. pylori virulence …

Historical and Molecular Perspectives on the Presence of Helicobacter pylori in Latin America: A Niche to Improve Gastric Cancer Risk Assessment

R González-Stegmaier, P Aguila-Torres… - International Journal of …, 2024 - mdpi.com
Helicobacter pylori (H. pylori) is responsible for causing chronic gastritis, which can cause
peptic ulcer and premalignant lesions such as atrophic gastritis, intestinal metaplasia, and …

[HTML][HTML] Helicobacter pylori eradication for primary prevention of gastric cancer: progresses and challenges

Z Liu, H Xu, W You, K Pan, W Li - Journal of the National Cancer Center, 2024 - Elsevier
Gastric cancer remains a significant global health challenge, causing a substantial number
of cancer-related deaths, particularly in China. While the exact causes of gastric cancer are …

Bioactive peptides as alternative treatment for Helicobacter pylori infection

G Franca-Oliveira, B Hernández-Ledesma… - Bioactive Compounds in …, 2024 - ffhdj.com
The infection and chronic inflammatory response generated by Helicobacter pylori is a
global health concern. This pathogen is characterized as a major risk factor in the …

Helicobacter pylori and gastric cancer: mechanisms and new perspectives

Y Duan, Y Xu, Y Dou, D Xu - Journal of Hematology & Oncology, 2025 - Springer
Gastric cancer remains a significant global health challenge, with Helicobacter pylori (H.
pylori) recognized as a major etiological agent, affecting an estimated 50% of the world's …

ACG clinical guideline: treatment of Helicobacter pylori infection

WD Chey, CW Howden, SF Moss… - Official journal of the …, 2024 - journals.lww.com
Helicobacter pylori is a prevalent, global infectious disease that causes dyspepsia, peptic
ulcer disease, and gastric cancer. The American College of Gastroenterology commissioned …

Genomic insights into the antimicrobial resistance and virulence of Helicobacter pylori isolates from gastritis patients in Pereira, Colombia

A Alvarez-Aldana, OO Ikhimiukor, YM Guaca-González… - BMC genomics, 2024 - Springer
Background Helicobacter pylori infects the stomach and/or small intestines in more than half
of the human population. Infection with H. pylori is the most common cause of chronic …