Hair follicles are essential appendages of the mammalian skin, as hair performs vital
functions of protection, thermoregulation and sensation. Hair follicles harbour exceptional …

Circadian clocks constitute the evolutionary molecular machinery that dictates the temporal
regulation of physiology to maintain homeostasis. Disruption of the circadian rhythm plays a …

The circadian clock imposes daily rhythms in cell proliferation, metabolism, inflammation
and DNA damage response,. Perturbations of these processes are hallmarks of cancer and …

The skin protects mammals from insults, infection and dehydration and enables
thermoregulation and sensory perception. Various skin-resident cells carry out these diverse …

Circadian rhythms are present in almost all cells and play a crucial role in regulating various
biological processes. Maintaining a stable circadian rhythm is essential for overall health …

Normal homeostatic functions of adult stem cells have rhythmic daily oscillations that are
believed to become arrhythmic during aging. Unexpectedly, we find that aged mice remain …

As the circadian clock regulates fundamental biological processes, disrupted clocks are
often observed in patients and diseased tissues. Determining the circadian time of the …

The cell cycle and the circadian clock operate as biological oscillators whose timed
functions are tightly regulated. Accumulating evidence illustrates the presence of molecular …

Circadian rhythms govern a large array of physiological and metabolic functions.
Perturbations of the daily cycle have been linked to elevated risk of develo** cancer as …

Circadian disruption has been identified as a risk factor for health disorders such as obesity,
cardiovascular disease, and cancer. Although epidemiological studies suggest an increased …