Ewing sarcoma: current management and future approaches through collaboration
N Gaspar, DS Hawkins, U Dirksen, IJ Lewis… - Journal of Clinical …, 2015 - ascopubs.org
Ewing sarcoma (ES) is an aggressive sarcoma of bone and soft tissue occurring at any age
with a peak incidence in adolescents and young adults. The treatment of ES relies on a …
with a peak incidence in adolescents and young adults. The treatment of ES relies on a …
Ewing sarcoma—diagnosis, treatment, clinical challenges and future perspectives
Ewing sarcoma, a highly aggressive bone and soft-tissue cancer, is considered a prime
example of the paradigms of a translocation-positive sarcoma: a genetically rather simple …
example of the paradigms of a translocation-positive sarcoma: a genetically rather simple …
Randomized controlled trial of interval-compressed chemotherapy for the treatment of localized Ewing sarcoma: a report from the Children's Oncology Group
RB Womer, DC West, MD Krailo… - Journal of Clinical …, 2012 - ascopubs.org
Purpose Chemotherapy with alternating vincristine-doxorubicin-cyclophosphamide and
ifosfamide-etoposide cycles and primary tumor treatment with surgery and/or radiation …
ifosfamide-etoposide cycles and primary tumor treatment with surgery and/or radiation …
Ewing's sarcoma
NJ Balamuth, RB Womer - The lancet oncology, 2010 - thelancet.com
Progress in the treatment of Ewing's sarcoma, the second most common bone tumour in
children and adolescents, has improved survival from about 10% in the period before …
children and adolescents, has improved survival from about 10% in the period before …
Improving quality and quantity of life for childhood cancer survivors globally in the twenty-first century
The contributions of cooperative groups to performing large-cohort clinical trials and long-
term survivorship studies have facilitated advances in treatment, supportive care and …
term survivorship studies have facilitated advances in treatment, supportive care and …
NCCN guidelines insights: bone cancer, version 2.2017
The NCCN Guidelines for Bone Cancer provide interdisciplinary recommendations for
treating chordoma, chondrosarcoma, giant cell tumor of bone, Ewing sarcoma, and …
treating chordoma, chondrosarcoma, giant cell tumor of bone, Ewing sarcoma, and …
Anthracycline-related cardiomyopathy after childhood cancer: role of polymorphisms in carbonyl reductase genes—a report from the Children's Oncology Group
JG Blanco, CL Sun, W Landier, L Chen… - Journal of Clinical …, 2012 - ascopubs.org
Purpose Carbonyl reductases (CBRs) catalyze reduction of anthracyclines to cardiotoxic
alcohol metabolites. Polymorphisms in CBR1 and CBR3 influence synthesis of these …
alcohol metabolites. Polymorphisms in CBR1 and CBR3 influence synthesis of these …
Common musculoskeletal tumors of childhood and adolescence
CAS Arndt, PS Rose, AL Folpe, NN Laack - Mayo Clinic Proceedings, 2012 - Elsevier
Osteosarcoma, Ewing sarcoma, and rhabdomyosarcoma are the most common malignant
musculoskeletal tumors in children and adolescents. Today, most patients can be cured …
musculoskeletal tumors in children and adolescents. Today, most patients can be cured …
R1507, a monoclonal antibody to the insulin-like growth factor 1 receptor, in patients with recurrent or refractory Ewing sarcoma family of tumors: results of a phase II …
AS Pappo, SR Patel, J Crowley, DK Reinke… - Journal of Clinical …, 2011 - ascopubs.org
Purpose The type 1 insulin-like growth factor 1 receptor (IGF-1R) has been implicated in the
pathogenesis of the Ewing sarcoma family of tumors (ESFT). We conducted a multicenter …
pathogenesis of the Ewing sarcoma family of tumors (ESFT). We conducted a multicenter …
Phase III trial adding vincristine-topotecan-cyclophosphamide to the initial treatment of patients with nonmetastatic Ewing sarcoma: A Children's Oncology Group …
PJ Leavey, NN Laack, MD Krailo, A Buxton… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE The primary aim of this phase III randomized trial was to test whether the addition
of vincristine, topotecan, and cyclophosphamide (VTC) to interval compressed …
of vincristine, topotecan, and cyclophosphamide (VTC) to interval compressed …