Current Approaches and Methods to Understand Acute Ischemic Stroke Treatment Using Aspiration Thrombectomy

P Patki, S Simon, F Costanzo, KB Manning - … Engineering and Technology, 2024 - Springer
Acute ischemic stroke occurs when a blood clot occludes a cerebral artery. Mechanical
interventions, primarily stent retrievers and aspiration thrombectomy, are used currently for …

Evaluating the accuracy of cerebrovascular computational fluid dynamics modeling through time-resolved experimental validation

CA Luisi, TL Witter, O Nikoubashman, M Wiesmann… - Scientific Reports, 2024 - nature.com
Accurate modeling of cerebral hemodynamics is crucial for better understanding the
hemodynamics of stroke, for which computational fluid dynamics (CFD) modeling is a viable …

Energy barriers govern catheter herniation during endovascular procedures: a 2.5 D vascular flow model analysis

MY Qiu, CB Suskin, MA Zayed… - Journal of the …, 2024 - royalsocietypublishing.org
Endovascular procedures rely on navigating guidewires, catheters and other devices
through tortuous vasculature to treat disease. A critical challenge in these procedures is …

Generation of a Virtual Cohort of Patients for in Silico Trials of Acute Ischemic Stroke Treatments

S Bridio, G Luraghi, A Ramella, JF Rodriguez Matas… - Applied Sciences, 2023 - mdpi.com
The development of in silico trials based on high-fidelity simulations of clinical procedures
requires the availability of large cohorts of three-dimensional (3D) patient-specific anatomy …

CT-based thrombus radiomics nomogram for predicting secondary embolization during mechanical thrombectomy for large vessel occlusion

S Yusuying, Y Lu, S Zhang, J Wang, J Chen… - Frontiers in …, 2023 - frontiersin.org
Background and aims Secondary embolization (SE) during mechanical thrombectomy (MT)
for cerebral large vessel occlusion (LVO) could reduce the anterior blood flow and worsen …

Impact of thrombus composition on virtual thrombectomy procedures using human clot analogues mechanical data

V Fregona, G Luraghi, B Fereidoonnezhad… - Journal of the …, 2025 - Elsevier
Endovascular thrombectomy (EVT) aims at restoring blood flow in case of acute ischemic
stroke by removing the thrombus occluding a large cerebral artery. During the procedure …

A multiscale computational framework to evaluate flow alterations during mechanical thrombectomy for treatment of ischaemic stroke

I Benemerito, A Mustafa, N Wang, AP Narata… - Frontiers in …, 2023 - frontiersin.org
The treatment of ischaemic stroke increasingly relies upon endovascular procedures known
as mechanical thrombectomy (MT), which consists in capturing and removing the clot with a …

Combined Technique for Internal Carotid Artery Terminus or Middle Cerebral Artery Occlusions in the ASTER2 Trial

A Sgreccia, JP Desilles, V Costalat, C Dargazanli… - Stroke, 2024 - Am Heart Assoc
BACKGROUND: The aim of this study was to report the results of a subgroup analysis of the
ASTER2 trial (Effect of Thrombectomy With Combined Contact Aspiration and Stent …

A novel methodology for the modeling of catheter aspiration in high-fidelity thrombectomy simulations

S Bridio, G Luraghi, A Dwivedi, R McCarthy… - Procedia Structural …, 2023 - Elsevier
The development of high-fidelity in silico simulations of the endovascular thrombectomy
(EVT) procedure, the treatment for acute ischemic stroke, is gaining importance for the …