5-Ene-4-thiazolidinones–An efficient tool in medicinal chemistry

D Kaminskyy, A Kryshchyshyn, R Lesyk - European journal of medicinal …, 2017 - Elsevier
The presented review is an attempt to summarize a huge volume of data on 5-ene-4-
thiazolidinones being a widely studied class of small molecules used in modern organic and …

Synthetic approaches, structure activity relationship and biological applications for pharmacologically attractive pyrazole/pyrazoline–thiazolidine-based hybrids

D Havrylyuk, O Roman, R Lesyk - European journal of medicinal chemistry, 2016 - Elsevier
The features of the chemistry of 4-thiazolidinone and pyrazole/pyrazolines as
pharmacologically attractive scaffolds were described in a number of reviews in which the …

A conceptual review of rhodanine: Current applications of antiviral drugs, anticancer and antimicrobial activities

SM Mousavi, M Zarei, SA Hashemi… - Artificial cells …, 2019 - Taylor & Francis
Rhodanines are accepted as advantaged heterocycles in medicinal chemistry as one of the
4-thiazolidinones subtypes. The aim of this paper is to analyze the features of rhodanine and …

Thiazolidine-2, 4-diones: Progress towards multifarious applications

VS Jain, DK Vora, CS Ramaa - Bioorganic & medicinal chemistry, 2013 - Elsevier
The promising activity shown by compounds containing thiazolidine-2, 4-dione nucleus in
numerous categories such as anti-hyperglycaemics, aldose reductase inhibitors, anti …

Synthesis, structural characterization, fukui functions, DFT calculations, molecular docking and biological efficiency of some novel heterocyclic systems

MA Ibrahim, AS Badran, MMA Attai… - Journal of Molecular …, 2024 - Elsevier
The electron deficient centers in α, β-unsaturated ketone 3 are C-2 and C= O of chromone
moieties as well as C= O and H-β of α, β-unsaturated ketone segment. To investigate the …

Ring opening ring closure reactions with 5, 9-diethyl-7-(chromon-3-yl)-7-hydroquinolino [3′, 4′: 5, 6] pyrano [3, 2-c] quinoline-6, 8 (5H, 9H)-dione with some 1, 2 …

AS Badran, A Ahmed, AI Nabeel, MA Ibrahim - Journal of Molecular …, 2024 - Elsevier
The chemical behaviour of electron deficient substrate 1 was investigated with some 1, 2-bi-
nucleophilic reagents. Reaction of substrate 1 with hydrazine derivatives namely hydrazine …

3-Formylchromones as diverse building blocks in heterocycles synthesis

TES Ali, MA Ibrahim, NM El-Gohary… - European Journal of …, 2013 - eurjchem.com
This review covers the chemical reactivity of 3-formylchromones towards condensation
reactions with a variety of carbon and nitrogen nucleophiles. Some chromone derivatives …

[HTML][HTML] Synthesis and antibacterial activity of new (2, 4-dioxothiazolidin-5-yl/ylidene) acetic acid derivatives with thiazolidine-2, 4-dione, rhodanine and 2 …

N Trotsko, U Kosikowska, A Paneth, M Wujec… - Saudi pharmaceutical …, 2018 - Elsevier
Abstract A series of new (2, 4-dioxothiazolidin-5-yl/ylidene) acetic acid derivatives with
thiazolidine-2, 4-dione, rhodanine and 2-thiohydantoin moiety (28–65) were synthesized by …

Synthesis of chromone-related pyrazole compounds

CMM Santos, VLM Silva, AMS Silva - Molecules, 2017 - mdpi.com
Chromones, six-membered oxygen heterocycles, and pyrazoles, five-membered two-
adjacent-nitrogen-containing heterocycles, represent two important classes of biologically …

[PDF][PDF] Ring opening ring closure reactions with 3-substituted chromones under nucleophilic conditions

MA Ibrahim, NM El-Gohary, S Said - Heterocycles, 2015 - triggered.edina.clockss.org
This review covers the ring opening ring closure (RORC) reactions of 3-substituted
chromones with a variety of nitrogen and carbon nucleophiles. The nucleophilic reagent …