Nucleation and growth are two important and entwined processes in materials synthesis and
engineering. While understanding of the fundamental mechanisms of the processes remain …

The elucidation of the three dimensional structure of biological macromolecules has
provided an important contribution to our current understanding of many basic mechanisms …

Organic molecules, such as pharmaceuticals, agro-chemicals and pigments, frequently form
several crystal polymorphs with different physicochemical properties. Finding polymorphs …

Computational crystal structure prediction (CSP) methods can now be applied to the smaller
pharmaceutical molecules currently in drug development. We review the recent uses of …

Here we review the polymorphism of organic molecules, obtained through batch
crystallization in solution carried out in a stirred vessel. Preferential formation of a …

Protein crystallization has been known since 1840 and can prove to be straightforward but,
in most cases, it constitutes a real bottleneck. This stimulated the birth of the …

This highlight investigates the different aspects of electric fields controlling crystallization,
focusing on strong electric fields. Application of both internal and external electric fields, as …

Highlights•Crystal structure prediction studies have been carried out with the pharmaceutical
industry.•Crystal energy landscapes can help to define solid form landscapes.•Crystal …

Process intensification (PI) provides great opportunities to drastically improve the
performance of chemical processes within many branches of chemical industry including the …

Applying a strong static electric field to supersaturated aqueous glycine solutions resulted in
the nucleation of the γ polymorph. This is the first report of a strong dc field inducing the …