Organic and biogenic nanocarriers as bio-friendly systems for bioactive compounds' delivery: state-of-the art and challenges

SM Petrovic, ME Barbinta-Patrascu - Materials, 2023 - mdpi.com
“Green” strategies to build up novel organic nanocarriers with bioperformance are modern
trends in nanotechnology. In this way, the valorization of bio-wastes and the use of living …

[HTML][HTML] Epithelial-mesenchymal transition in cancer: A focus on itraconazole, a hedgehog inhibitor

AM Kulkarni, PKR Gayam, BT Baby… - Biochimica et Biophysica …, 2025 - Elsevier
Cancer, and the resulting mortality from it, is an ever-increasing concern in global health.
Cancer mortality stems from the metastatic progression of the disease, by dissemination of …

Therapeutic potential of limonene-based syringic acid nanoemulsion: Enhanced ex-vivo cutaneous deposition and clinical anti-psoriatic efficacy

N Assalem, H Abd-Allah, MH Ragaie, SS Ahmed… - International Journal of …, 2024 - Elsevier
Nanoemulsions have carved their position in topical delivery owing to their peculiar features
of forming a uniform film on the skin and conquering stratum corneum barrier and hence …

Engineered triamcinolone acetonide loaded glycerosomes as a novel ear delivery system for the treatment of otitis media

M Magdy, E Elmowafy, MIA El-Assal… - International Journal of …, 2022 - Elsevier
Ear-oriented therapeutics vehiculation strategies are requisites for effective treatment of
various otic ailments including otitis media (OM). Conquering minimal permeability of the …

Microsponges-mediated targeted topical delivery of rosemary oil for hair growth promotion: optimization and in-vivo studies

RM Yehia, C Lamie, DA Attia - Pharmaceutical Development and …, 2024 - Taylor & Francis
Individuals experiencing hair loss, irrespective of gender, confront significant psychological
challenges. This study explores the untapped potential of rosemary oil (ROS) to stimulate …

Formulation and optimization of surfactant-modified chitosan nanoparticles loaded with cefdinir for novel topical drug delivery: Elevating wound healing efficacy with …

MA Badie, MH Teaima, MA El-Nabarawi… - International Journal of …, 2024 - Elsevier
Burn wounds remain a significant global health concern, frequently exacerbated by bacterial
infections that hinder healing and raise morbidity rates. Cefdinir, a third-generation …

[HTML][HTML] Tackling acne vulgaris by fabrication of tazarotene-loaded essential oil-based microemulsion: In vitro and in vivo evaluation

NM Badawi, RM Yehia, C Lamie… - International Journal of …, 2023 - Elsevier
This study aimed to formulate and optimize an anti-acne drug namely tazarotene (TZR) in
essential oil-based microemulsion (ME) using either Jasmine oil (Jas) or Jojoba oil (Joj) …

Assessment of antifungal efficacy of itraconazole loaded aspasomal cream: comparative clinical study

C Lamie, E Elmowafy, MH Ragaie, DA Attia… - Drug Delivery, 2022 - Taylor & Francis
Topical conveyance of antifungal agents like itraconazole ITZ has been giving good grounds
for expecting felicitous antifungal medicines. The defiance of topical delivery of this poorly …

Gamma oryzanol loaded into micelle-core/chitosan-shell: from translational nephroprotective potential to emphasis on sirtuin-1 associated machineries

E Elmowafy, MO El-Derany, L Casettari… - International Journal of …, 2023 - Elsevier
Gamma oryzanol (ORZ) is a nutraceutical that is poorly water soluble with poor intestinal
absorption. In the current work, ORZ was nanoformulated into uncoated and chitosan coated …

Development of gallic acid loaded composite nanovesicles for the topical treatment of acne: optimization, characterization, and clinical investigation

S Hatem, NH Moftah, MH Ragai… - Pharmaceutical …, 2024 - Taylor & Francis
Gallic acid (GA) proved to produce desired effects topically in the treatment of acne, through
its antibacterial, anti-inflammatory and antioxidant characteristics. In the current work …