Interconnections between inflammageing and immunosenescence during ageing
Acute inflammation is a physiological response to injury or infection, with a cascade of steps
that ultimately lead to the recruitment of immune cells to clear invading pathogens and heal …
that ultimately lead to the recruitment of immune cells to clear invading pathogens and heal …
AGE/RAGE in diabetic kidney disease and ageing kidney
XQ Wu, DD Zhang, YN Wang, YQ Tan, XY Yu… - Free Radical Biology …, 2021 - Elsevier
Diabetic kidney disease (DKD) is the primary cause of chronic kidney disease that inevitably
progress to end-stage kidney disease. Intervention strategies such as blood glucose control …
progress to end-stage kidney disease. Intervention strategies such as blood glucose control …
Advanced glycation end products and diabetes mellitus: mechanisms and perspectives
Persistent hyperglycemic state in type 2 diabetes mellitus leads to the initiation and
progression of non-enzymatic glycation reaction with proteins and lipids and nucleic acids …
progression of non-enzymatic glycation reaction with proteins and lipids and nucleic acids …
Advanced glycation end products and their effect on vascular complications in type 2 diabetes mellitus
J Lee, JS Yun, SH Ko - Nutrients, 2022 - mdpi.com
Diabetes is well established as a chronic disease with a high health burden due to mortality
or morbidity from the final outcomes of vascular complications. An increased duration of …
or morbidity from the final outcomes of vascular complications. An increased duration of …
IDF Diabetes Atlas: Diabetes and oral health–A two-way relationship of clinical importance
WS Borgnakke - Diabetes research and clinical practice, 2019 - Elsevier
The current scientific evidence for the bi-directional associations between oral health and
diabetes is summarized. The universal biologic mechanisms and demographic and …
diabetes is summarized. The universal biologic mechanisms and demographic and …
[HTML][HTML] Targeting HMGB1: an available therapeutic strategy for breast cancer therapy
H Dong, L Zhang, S Liu - International journal of biological …, 2022 - ncbi.nlm.nih.gov
HMGB1 is a member of highly conserved high mobility group protein superfamily with
intracellular and extracellular distribution. Abnormal HMGB1 levels are frequently …
intracellular and extracellular distribution. Abnormal HMGB1 levels are frequently …
The role of phosphatidylserine on the membrane in immunity and blood coagulation
J Wang, C Yu, J Zhuang, W Qi, J Jiang, X Liu… - Biomarker …, 2022 - Springer
The negatively charged aminophospholipid, phosphatidylserine (PtdSer), is located in the
inner leaflet of the plasma membrane in normal cells, and may be exposed to the outer …
inner leaflet of the plasma membrane in normal cells, and may be exposed to the outer …
Advancing the understanding of diabetic encephalopathy through unravelling pathogenesis and exploring future treatment perspectives
Diabetic encephalopathy (DE), a significant micro-complication of diabetes, manifests as
neurochemical, structural, behavioral, and cognitive alterations. This condition is especially …
neurochemical, structural, behavioral, and cognitive alterations. This condition is especially …
Insulin/IGF axis and the Receptor for Advanced Glycation End Products: role in meta-inflammation and potential in cancer therapy
In metabolic conditions such as obesity and diabetes, which are associated with
deregulated signaling of the insulin/insulin-like growth factor system (IIGFs), inflammation …
deregulated signaling of the insulin/insulin-like growth factor system (IIGFs), inflammation …
A novel role of Nano selenium and sildenafil on streptozotocin-induced diabetic nephropathy in rats by modulation of inflammatory, oxidative, and apoptotic pathways
Aims The present study aimed to investigate the effect of nano selenium, sildenafil, and their
combination on inflammation, oxidative stress, and apoptosis in streptozotocin-induced …
combination on inflammation, oxidative stress, and apoptosis in streptozotocin-induced …