Microbiota medicine: towards clinical revolution

P Gebrayel, C Nicco, S Al Khodor, J Bilinski… - Journal of translational …, 2022 - Springer
The human gastrointestinal tract is inhabited by the largest microbial community within the
human body consisting of trillions of microbes called gut microbiota. The normal flora is the …

International consensus conference on stool banking for faecal microbiota transplantation in clinical practice

G Cammarota, G Ianiro, CR Kelly, BH Mullish… - Gut, 2019 - gut.bmj.com
Although faecal microbiota transplantation (FMT) has a well-established role in the treatment
of recurrent Clostridioides difficile infection (CDI), its widespread dissemination is limited by …

The evolution of the use of faecal microbiota transplantation and emerging therapeutic indications

JR Allegretti, BH Mullish, C Kelly, M Fischer - The Lancet, 2019 - thelancet.com
Developments in high-throughput microbial genomic sequencing and other systems biology
techniques have given novel insight into the potential contribution of the gut microbiota to …

Commensal consortia decolonize Enterobacteriaceae via ecological control

M Furuichi, T Kawaguchi, MM Pust, K Yasuma-Mitobe… - Nature, 2024 - nature.com
Persistent colonization and outgrowth of potentially pathogenic organisms in the intestine
can result from long-term antibiotic use or inflammatory conditions, and may perpetuate …

Phages and their potential to modulate the microbiome and immunity

S Federici, SP Nobs, E Elinav - Cellular & molecular immunology, 2021 - nature.com
Bacteriophages (hence termed phages) are viruses that target bacteria and have long been
considered as potential future treatments against antibiotic-resistant bacterial infection …

Fecal microbiota transplantation: screening and selection to choose the optimal donor

S Bibbò, CR Settanni, S Porcari, E Bocchino… - Journal of Clinical …, 2020 - mdpi.com
In the past decade, fecal microbiota transplantation (FMT) has rapidly spread worldwide in
clinical practice as a highly effective treatment option against recurrent Clostridioides difficile …

Intestinal colonization with multidrug-resistant Enterobacterales: screening, epidemiology, clinical impact, and strategies to decolonize carriers

EI Campos-Madueno, M Moradi, Y Eddoubaji… - European Journal of …, 2023 - Springer
The clinical impact of infections due to extended-spectrum β-lactamase (ESBL)-and/or
carbapenemase-producing Enterobacterales (Ent) has reached dramatic levels worldwide …

Outbreak of Pseudomonas aeruginosa producing VIM carbapenemase in an intensive care unit and its termination by implementation of waterless patient care

G Catho, R Martischang, F Boroli, MN Chraïti, Y Martin… - Critical Care, 2021 - Springer
Background Long-term outbreaks of multidrug-resistant Gram-negative bacilli related to
hospital-building water systems have been described. However, successful mitigation …

The role of the microbiota in the management of intensive care patients

P Szychowiak, K Villageois-Tran, J Patrier… - Annals of intensive …, 2022 - Springer
The composition of the gut microbiota is highly dynamic and changes according to various
conditions. The gut microbiota mainly includes difficult-to-cultivate anaerobic bacteria, hence …

Gut microbiota, antibiotic therapy and antimicrobial resistance: a narrative review

B Pilmis, A Le Monnier, JR Zahar - Microorganisms, 2020 - mdpi.com
Antimicrobial resistance is a major concern. Epidemiological studies have demonstrated
direct relationships between antibiotic consumption and emergence/dissemination of …