Self-healing injectable hydrogels for tissue regeneration

P Bertsch, M Diba, DJ Mooney… - Chemical …, 2022 - ACS Publications
Biomaterials with the ability to self-heal and recover their structural integrity offer many
advantages for applications in biomedicine. The past decade has witnessed the rapid …

[HTML][HTML] Supramolecular engineering of hydrogels for drug delivery

S Bernhard, MW Tibbitt - Advanced Drug Delivery Reviews, 2021 - Elsevier
Supramolecular binding motifs are increasingly employed in the design of biomaterials. The
ability to rationally engineer specific yet reversible associations into polymer networks with …

[HTML][HTML] An injectable conductive hydrogel with dual responsive release of rosmarinic acid improves cardiac function and promotes repair after myocardial infarction

L Zhang, Z Bei, T Li, Z Qian - Bioactive Materials, 2023 - Elsevier
Myocardial infarction (MI) causes irreversible damage to the heart muscle, seriously
threatening the lives of patients. Injectable hydrogels have attracted extensive attention in …

Recent progress on polysaccharide-based hydrogels for controlled delivery of therapeutic biomolecules

MI Rial-Hermida, A Rey-Rico… - ACS Biomaterials …, 2021 - ACS Publications
A plethora of applications using polysaccharides have been developed in recent years due
to their availability as well as their frequent nontoxicity and biodegradability. These polymers …

Immunomodulatory biomaterials and their application in therapies for chronic inflammation-related diseases

JR Nakkala, Z Li, W Ahmad, K Wang, C Gao - Acta Biomaterialia, 2021 - Elsevier
The degree of tissue injuries such as the level of scarring or organ dysfunction, and the
immune response against them primarily determine the outcome and speed of healing …

Prolonged codelivery of hemagglutinin and a TLR7/8 agonist in a supramolecular polymer–nanoparticle hydrogel enhances potency and breadth of influenza …

GA Roth, OM Saouaf, AAA Smith, EC Gale… - ACS biomaterials …, 2021 - ACS Publications
The sustained release of vaccine cargo has been shown to improve humoral immune
responses to challenging pathogens such as influenza. Extended codelivery of antigen and …

Biologics and their delivery systems: Trends in myocardial infarction

MA Borrelli, HR Turnquist, SR Little - Advanced drug delivery reviews, 2021 - Elsevier
Cardiovascular disease is the leading cause of death around the world, in which myocardial
infarction (MI) is a precipitating event. However, current therapies do not adequately address …

[HTML][HTML] Cardiac tissue engineering for myocardial infarction treatment

P Gil-Cabrerizo, I Scacchetti, E Garbayo… - European Journal of …, 2023 - Elsevier
Myocardial infarction is one of the major causes of morbidity and mortality worldwide.
Current treatments can relieve the symptoms of myocardial ischemia but cannot repair the …

Biomaterials loaded with growth factors/cytokines and stem cells for cardiac tissue regeneration

S Smagul, Y Kim, A Smagulova, K Raziyeva… - International journal of …, 2020 - mdpi.com
Myocardial infarction causes cardiac tissue damage and the release of damage-associated
molecular patterns leads to activation of the immune system, production of inflammatory …

Self-assembled, dilution-responsive hydrogels for enhanced thermal stability of insulin biopharmaceuticals

CM Meis, EE Salzman, CL Maikawa… - ACS Biomaterials …, 2020 - ACS Publications
Biotherapeutics currently dominate the landscape of new drugs because of their exceptional
potency and selectivity. Yet, the intricate molecular structures that give rise to these …