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Single-vesicle assays using liposomes and cell-derived vesicles: from modeling complex membrane processes to synthetic biology and biomedical applications
The plasma membrane is of central importance for defining the closed volume of cells in
contradistinction to the extracellular environment. The plasma membrane not only serves as …
contradistinction to the extracellular environment. The plasma membrane not only serves as …
Luminescence lifetime imaging of three-dimensional biological objects
ABSTRACT A major focus of current biological studies is to fill the knowledge gaps between
cell, tissue and organism scales. To this end, a wide array of contemporary optical analytical …
cell, tissue and organism scales. To this end, a wide array of contemporary optical analytical …
Laurdan and Di-4-ANEPPDHQ probe different properties of the membrane
Lipid packing is a crucial feature of cellular membranes. Quantitative analysis of membrane
lipid packing can be achieved using polarity sensitive probes whose emission spectrum …
lipid packing can be achieved using polarity sensitive probes whose emission spectrum …
A Rotational BODIPY Nucleotide: An Environment‐Sensitive Fluorescence‐Lifetime Probe for DNA Interactions and Applications in Live‐Cell Microscopy
Fluorescent probes for detecting the physical properties of cellular structures have become
valuable tools in life sciences. The fluorescence lifetime of molecular rotors can be used to …
valuable tools in life sciences. The fluorescence lifetime of molecular rotors can be used to …
Laurdan discerns lipid membrane hydration and cholesterol content
Studies of biological membrane heterogeneity particularly benefit from the use of the
environment-sensitive fluorescent probe Laurdan, for which shifts in the emission, produced …
environment-sensitive fluorescent probe Laurdan, for which shifts in the emission, produced …
With or without rafts? Alternative views on cell membranes
The fundamental mechanisms of protein and lipid organization at the plasma membrane
have continued to engage researchers for decades. Among proposed models, one idea has …
have continued to engage researchers for decades. Among proposed models, one idea has …
GM1 Ganglioside Inhibits β‐Amyloid Oligomerization Induced by Sphingomyelin
Abstract β‐Amyloid (Aβ) oligomers are neurotoxic and implicated in Alzheimer's disease.
Neuronal plasma membranes may mediate formation of Aβ oligomers in vivo. Membrane …
Neuronal plasma membranes may mediate formation of Aβ oligomers in vivo. Membrane …
Graphene oxide-based fluorescent biosensors for pathogenic bacteria detection: A review
S Liu, F Lu, S Chen, Y Ning - Analytica Chimica Acta, 2024 - Elsevier
Background Pathogenic bacteria are widespread in nature and can cause infections and
various complications, thereby posing a severe risk to public health. Therefore, simple …
various complications, thereby posing a severe risk to public health. Therefore, simple …
Cholesterol under oxidative stress—How lipid membranes sense oxidation as cholesterol is being replaced by oxysterols
The behavior of oxysterols in phospholipid membranes and their effects on membrane
properties were investigated by means of dynamic light scattering, fluorescence …
properties were investigated by means of dynamic light scattering, fluorescence …
A unifying framework for amyloid-mediated membrane damage: The lipid-chaperone hypothesis
Over the past thirty years, researchers have highlighted the role played by a class of proteins
or polypeptides that forms pathogenic amyloid aggregates in vivo, including i) the amyloid …
or polypeptides that forms pathogenic amyloid aggregates in vivo, including i) the amyloid …