The microbiota–gut–brain axis in Huntington's disease: pathogenic mechanisms and therapeutic targets
Huntington's disease (HD) is a currently incurable neurogenerative disorder and is typically
characterized by progressive movement disorder (including chorea), cognitive deficits …
characterized by progressive movement disorder (including chorea), cognitive deficits …
Metabolomics: an emerging “omics” platform for systems biology and its implications for Huntington disease research
Huntington's disease (HD) is a progressive, fatal neurodegenerative disease characterized
by motor, cognitive, and psychiatric symptoms. The precise mechanisms of HD progression …
by motor, cognitive, and psychiatric symptoms. The precise mechanisms of HD progression …
A natural history of NAA15-related neurodevelopmental disorder through adolescence
R Makwana, C Christ, R Patel, E Marchi, R Harpell… - medRxiv, 2024 - pmc.ncbi.nlm.nih.gov
NAA15 is a member of the NatA N-terminal acetyltransferase complex, which also includes
the NAA10 enzymatic sub-unit. Individuals with variants in the NAA15 coding region develop …
the NAA10 enzymatic sub-unit. Individuals with variants in the NAA15 coding region develop …
[HTML][HTML] Exploring the potential of plasma and adipose mesenchymal stem cell-derived extracellular vesicles as novel platforms for neuroinflammation therapy
RO Silva, M Haddad, H Counil, C Zaouter… - Journal of Controlled …, 2025 - Elsevier
Persistent reactive oxygen species (ROS) and neuroinflammation contribute to the onset
and progression of neurodegenerative diseases, underscoring the need for targeted …
and progression of neurodegenerative diseases, underscoring the need for targeted …
Serum metabolomic signatures of patients with rare neurogenetic diseases: an insight into potential biomarkers and treatment targets
Introduction To further advance our understanding of Muscular Dystrophies (MDs) and
Spinocerebellar Ataxias (SCAs), it is necessary to identify the biological patterns associated …
Spinocerebellar Ataxias (SCAs), it is necessary to identify the biological patterns associated …
[HTML][HTML] Peripheral and central elevation of IL-8 in patients with Huntington's disease
Abstract Objectives Huntington's Disease (HD) is a debilitating neurodegenerative condition
characterized by motor, cognitive and psychiatric abnormalities. Immune hyperactivity and …
characterized by motor, cognitive and psychiatric abnormalities. Immune hyperactivity and …
The interplay between gut microbiota composition and dementia
R Ghannadzadeh Kermani pour… - Reviews in the …, 2025 - degruyter.com
Recently, researchers have been interested in the potential connection between gut
microbiota composition and various neuropsychological disorders. Dementia significantly …
microbiota composition and various neuropsychological disorders. Dementia significantly …
Brain–Periphery Interactions in Huntington's Disease: Mediators and Lifestyle Interventions
Prominent pathological features of Huntington's disease (HD) are aggregations of mutated
Huntingtin protein (mHtt) in the brain and neurodegeneration, which causes characteristic …
Huntingtin protein (mHtt) in the brain and neurodegeneration, which causes characteristic …
[HTML][HTML] Advances in Huntington's Disease Biomarkers: A 10-Year Bibliometric Analysis and a Comprehensive Review
S Aqel, J Ahmad, I Saleh, A Fathima, AA Al Thani… - Biology, 2025 - mdpi.com
Neurodegenerative disorders (NDs) cause progressive neuronal loss and are a significant
public health concern, with NDs projected to become the second leading global cause of …
public health concern, with NDs projected to become the second leading global cause of …
[PDF][PDF] Influence of dietary patterns in the pathophysiology of Huntington's Disease: A literature review
U Ansari, D Nadora, M Alam, J Wen, S Asad… - AIMS …, 2024 - aimspress.com
Influence of dietary patterns in the pathophysiology of Huntington’s Disease: A literature review
Page 1 AIMS Neuroscience, 11 (2): 63–75. DOI: 10.3934/Neuroscience.2024005 Received: 01 …
Page 1 AIMS Neuroscience, 11 (2): 63–75. DOI: 10.3934/Neuroscience.2024005 Received: 01 …