Comparative protein structure modeling predicts the three‐dimensional structure of a given
protein sequence (target) based primarily on its alignment to one or more proteins of known …

Antiphospholipid antibodies (Abs) are associated with thrombosis and are a risk factor for
recurrent pregnancy loss and obstetric complications in patients with the antiphospholipid …

Adsorption of serum proteins to the liposomal surface plays a critical role in the clearance of
liposomes from the blood circulation. In this review, we will discuss the role of the liposomal …

Understanding nanoparticle–protein interactions is a crucial issue in the development of
targeted nanomaterial delivery. Besides unraveling the composition of the nanoparticle's …

Anti–β2–glycoprotein I antibodies are known to have a heterogeneous reactivity against β2–
glycoprotein I. We performed this study to characterize the epitope on β2–glycoprotein I to …

Human β 2‐glycoprotein I is a heavily glycosylated five‐domain plasma membrane‐
adhesion protein, which has been implicated in blood coagulation and clearance of …

Objective To clarify the association of autoantibodies against prothrombin with the clinical
manifestations of the antiphospholipid syndrome (APS) and with the presence of lupus …

Patients with prolonged clotting times caused by lupus anticoagulant (LAC) are at risk for
thrombosis. This paradoxal association is not understood. LAC is frequently caused by anti …

Beta-2 glycoprotein I (β2GPI) is the principal target of autoantibodies in the antiphospholipid
syndrome (APS). It is abundant in human plasma and shares high homology between …

Objective Pathogenic antiphospholipid antibodies (aPL) bind the self antigen N‐terminal
domain (domain I) of β2‐glycoprotein I (β2GPI), with residues G40–R43 being important …