Involvement of astrocytes in Alzheimer's disease from a neuroinflammatory and oxidative stress perspective
Alzheimer disease (AD) is a frequent and devastating neurodegenerative disease in
humans, but still no curative treatment has been developed. Although many explicative …
humans, but still no curative treatment has been developed. Although many explicative …
A review on neuroimaging-based classification studies and associated feature extraction methods for Alzheimer's disease and its prodromal stages
Neuroimaging has made it possible to measure pathological brain changes associated with
Alzheimer's disease (AD) in vivo. Over the past decade, these measures have been …
Alzheimer's disease (AD) in vivo. Over the past decade, these measures have been …
Clearance systems in the brain—implications for Alzheimer disease
Accumulation of toxic protein aggregates—amyloid-β (Aβ) plaques and
hyperphosphorylated tau tangles—is the pathological hallmark of Alzheimer disease (AD) …
hyperphosphorylated tau tangles—is the pathological hallmark of Alzheimer disease (AD) …
Defective mitophagy and synaptic degeneration in Alzheimer's disease: Focus on aging, mitochondria and synapse
H Morton, S Kshirsagar, E Orlov, LE Bunquin… - Free Radical Biology …, 2021 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
memory loss and multiple cognitive impairments. AD is marked by multiple cellular changes …
memory loss and multiple cognitive impairments. AD is marked by multiple cellular changes …
[HTML][HTML] Functions and dysfunctions of nitric oxide in brain
P Picón-Pagès, J Garcia-Buendia, FJ Munoz - Biochimica et Biophysica …, 2019 - Elsevier
Nitric oxide (NO) works as a retrograde neurotransmitter in synapses, allows the brain blood
flow and also has important roles in intracellular signaling in neurons from the regulation of …
flow and also has important roles in intracellular signaling in neurons from the regulation of …
β-amyloid protein induces mitophagy-dependent ferroptosis through the CD36/PINK/PARKIN pathway leading to blood–brain barrier destruction in Alzheimer's …
J Li, M Li, Y Ge, J Chen, J Ma, C Wang, M Sun… - Cell & Bioscience, 2022 - Springer
Introduction Blood–brain barrier (BBB) dysfunction may occur at the onset of Alzheimer's
disease (AD). Pericytes are a vital part of the neurovascular unit and the BBB, acting as …
disease (AD). Pericytes are a vital part of the neurovascular unit and the BBB, acting as …
[HTML][HTML] Decoding Alzheimer's disease from perturbed cerebral glucose metabolism: implications for diagnostic and therapeutic strategies
Z Chen, C Zhong - Progress in neurobiology, 2013 - Elsevier
Alzheimer's disease (AD) is an age-related devastating neurodegenerative disorder, which
severely impacts on the global economic development and healthcare system. Though AD …
severely impacts on the global economic development and healthcare system. Though AD …
Association of insulin resistance with cerebral glucose uptake in late middle–aged adults at risk for Alzheimer disease
Importance Converging evidence suggests that Alzheimer disease (AD) involves insulin
signaling impairment. Patients with AD and individuals at risk for AD show reduced glucose …
signaling impairment. Patients with AD and individuals at risk for AD show reduced glucose …
Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the …
P Lewczuk, P Riederer, SE O'bryant… - The world journal of …, 2018 - Taylor & Francis
In the 12 years since the publication of the first Consensus Paper of the WFSBP on
biomarkers of neurodegenerative dementias, enormous advancement has taken place in …
biomarkers of neurodegenerative dementias, enormous advancement has taken place in …
Neuroimaging biomarkers for Alzheimer's disease
F Márquez, MA Yassa - Molecular neurodegeneration, 2019 - Springer
Currently, over five million Americans suffer with Alzheimer's disease (AD). In the absence of
a cure, this number could increase to 13.8 million by 2050. A critical goal of biomedical …
a cure, this number could increase to 13.8 million by 2050. A critical goal of biomedical …