The comparison of the immunological state of pregnancy to an immunosuppressed host–
graft model continues to lead research and clinical practice to ill-defined approaches. This …

The endoplasmic reticulum (ER) is an essential organelle in eukaryotic cells for the storage
and regulated release of calcium and as the entrance to the secretory pathway. Protein …

The hallmarks of cancer described by Hanahan and Weinberg have proved seminal in our
understanding of cancer's common traits and in rational drug design. Not free of critique and …

Risks of tumor recurrence after surgical resection have been known for decades, but the
mechanisms underlying treatment failures remain poorly understood. Neutrophils, first-line …

Oral squamous cell carcinoma (OSCC) is a lethal disease whose incidence is increasing.
Epidemiologic studies demonstrate an association between periodontitis and oral cancer …

It is well admitted that the link between chronic inflammation and cancer involves cytokines
and mediators of inflammatory pathways, which act during the different steps of …

A transmembrane protein (TMEM) is a type of protein that spans biological membranes.
Many of them extend through the lipid bilayer of the plasma membrane but others are …

MicroRNAs (miRNAs) are recognized as being central players in many biological processes
and cellular pathways. Their roles in disease have been highlighted first by observation of …

Toll-like receptors (TLRs) are a family of transmembrane receptors that recognize various
pathogen-and damage-associated molecular pattern molecules playing an important role in …

During mammalian pregnancy maternal-fetal tolerance involves a number of
immunosuppressive factors produced by placenta. Recently, placenta-derived exosomes …