Mammalian alpha beta hydrolase domain (ABHD) proteins: Lipid metabolizing enzymes at the interface of cell signaling and energy metabolism

CC Lord, G Thomas, JM Brown - … et Biophysica Acta (BBA)-Molecular and …, 2013‏ - Elsevier
Dysregulation of lipid metabolism underlies many chronic diseases such as obesity,
diabetes, cardiovascular disease, and cancer. Therefore, understanding enzymatic …

α/β-Hydrolase domain (ABHD) inhibitors as new potential therapeutic options against lipid-related diseases

G Bononi, T Tuccinardi, F Rizzolio… - Journal of medicinal …, 2021‏ - ACS Publications
Much of the experimental evidence in the literature has linked altered lipid metabolism to
severe diseases such as cancer, obesity, cardiovascular pathologies, diabetes, and …

Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species

KR Bradnam, JN Fass, A Alexandrov, P Baranay… - …, 2013‏ - academic.oup.com
Background The process of generating raw genome sequence data continues to become
cheaper, faster, and more accurate. However, assembly of such data into high-quality …

Genome-wide association study for feed efficiency and growth traits in US beef cattle

CM Seabury, DL Oldeschulte, M Saatchi, JE Beever… - BMC genomics, 2017‏ - Springer
Background Single nucleotide polymorphism (SNP) arrays for domestic cattle have
catalyzed the identification of genetic markers associated with complex traits for inclusion in …

Genome-wide association studies for 30 haematological and blood clinical-biochemical traits in Large White pigs reveal genomic regions affecting intermediate …

S Bovo, G Mazzoni, F Bertolini, G Schiavo… - Scientific reports, 2019‏ - nature.com
Haematological and clinical-biochemical parameters are considered indicators of the
physiological/health status of animals and might serve as intermediate phenotypes to link …

Identification of genomic regions associated with feed efficiency in Nelore cattle

PSN De Oliveira, ASM Cesar, ML do Nascimento… - BMC genetics, 2014‏ - Springer
Background Feed efficiency is jointly determined by productivity and feed requirements, both
of which are economically relevant traits in beef cattle production systems. The objective of …

A genomewide association study for average daily gain in Italian Large White pigs

L Fontanesi, G Schiavo, G Galimberti… - Journal of animal …, 2014‏ - academic.oup.com
Average daily gain is an important target trait in pig breeding programs. In this study we
performed a genomewide association study for ADG in Italian Large White pigs using a …

A genome wide association study for backfat thickness in Italian Large White pigs highlights new regions affecting fat deposition including neuronal genes

L Fontanesi, G Schiavo, G Galimberti, DG Calò, E Scotti… - BMC genomics, 2012‏ - Springer
Background Carcass fatness is an important trait in most pig breeding programs. Following
market requests, breeding plans for fresh pork consumption are usually designed to reduce …

Whole genome re-sequencing reveals recent signatures of selection in three strains of farmed Nile tilapia (Oreochromis niloticus)

MI Cádiz, ME Lopez, D Diaz-Dominguez, G Caceres… - Scientific reports, 2020‏ - nature.com
Nile tilapia belongs to the second most cultivated group of fish in the world, mainly because
of its favorable characteristics for production. Genetic improvement programs and …

Genome-wide association study of meat quality traits in a three-way crossbred commercial pig population

G Gao, N Gao, S Li, W Kuang, L Zhu, W Jiang… - Frontiers in …, 2021‏ - frontiersin.org
Meat quality is an important trait for pig-breeding programs aiming to meet consumers'
demands. Geneticists must improve meat quality based on their understanding of the …