Cholesterol is a crucial component of membrane bilayers by regulating their structural and
functional properties. Cholesterol traffics to different cellular compartments including …

The plasma membrane of eukaryotic cells is not a simple sheet of lipids and proteins but is
differentiated into subdomains with crucial functions. Caveolae, small pits in the plasma …

INTRODUCTION In all eukaryotic cells, lipid droplets (LDs) store and supply essential lipids
to produce signaling molecules, membrane building blocks, and metabolic energy. The LD …

Multidrug resistance remains a great challenge for cancer chemotherapy. Herein, a
biomimetic drug delivery system based on lemon‐derived extracellular vesicles (EVs) …

Type I interferon restrains interleukin-1β (IL-1β)-driven inflammation in macrophages by
upregulating cholesterol-25-hydroxylase (Ch25h) and repressing SREBP transcription …

Glutathione (GSH) is the main non-protein thiol in cells whose functions are dependent on
the redox-active thiol of its cysteine moiety that serves as a cofactor for a number of …

Caveolae are submicroscopic, plasma membrane pits that are abundant in many
mammalian cell types. The past few years have seen a quantum leap in our understanding …

Aims: Iron metabolism is involved in many biological processes in the brain. Alterations in
iron homeostasis have been associated with several neurodegenerative disorders. Instead …

Abstract Caveolin-1 (CAV1) is an oncogenic membrane protein associated with endocytosis,
extracellular matrix organisation, cholesterol distribution, cell migration and signaling …

Congenital generalized lipodystrophy (CGL) is a heterogeneous autosomal recessive
disorder characterized by a near complete lack of adipose tissue from birth and, later in life …