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Microbiome and human health: current understanding, engineering, and enabling technologies
The human microbiome is composed of a collection of dynamic microbial communities that
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …
inhabit various anatomical locations in the body. Accordingly, the coevolution of the …
Engineered living materials for advanced diseases therapy
X Dong, W Wu, P Pan, XZ Zhang - Advanced Materials, 2023 - Wiley Online Library
Natural living materials serving as biotherapeutics exhibit great potential for treating various
diseases owing to their immunoactivity, tissue targeting, and other biological activities. In this …
diseases owing to their immunoactivity, tissue targeting, and other biological activities. In this …
Cloaking mesoporous polydopamine with bacterial membrane vesicles to amplify local and systemic antitumor immunity
W Chen, Y Song, S Bai, C He, Z Guo, Y Zhu, Z Zhang… - ACS …, 2023 - ACS Publications
As adjuvants or antigens, bacterial membranes have been widely used in recent
antibacterial and antitumor research, but they are often injected multiple times to achieve …
antibacterial and antitumor research, but they are often injected multiple times to achieve …
Microbe-material hybrids for therapeutic applications
As natural living substances, microorganisms have emerged as useful resources in
medicine for creating microbe-material hybrids ranging from nano to macro dimensions. The …
medicine for creating microbe-material hybrids ranging from nano to macro dimensions. The …
Topical drug delivery strategies for enhancing drug effectiveness by skin barriers, drug delivery systems and individualized dosing
L Zhao, J Chen, B Bai, G Song, J Zhang, H Yu… - Frontiers in …, 2024 - frontiersin.org
Topical drug delivery is widely used in various diseases because of the advantages of not
passing through the gastrointestinal tract, avoiding gastrointestinal irritation and hepatic first …
passing through the gastrointestinal tract, avoiding gastrointestinal irritation and hepatic first …
Novel strategies for modulating the gut microbiome for cancer therapy
Recent advancements in genomics, transcriptomics, and metabolomics have significantly
advanced our understanding of the human gut microbiome and its impact on the efficacy …
advanced our understanding of the human gut microbiome and its impact on the efficacy …
Novel approaches in IBD therapy: Targeting the gut microbiota-bile acid axis
Y Pan, H Zhang, M Li, T He, S Guo, L Zhu, J Tan… - Gut …, 2024 - Taylor & Francis
Inflammatory bowel disease (IBD) is a chronic and recurrent condition affecting the
gastrointestinal tract. Disturbed gut microbiota and abnormal bile acid (BA) metabolism are …
gastrointestinal tract. Disturbed gut microbiota and abnormal bile acid (BA) metabolism are …
The potential use of bacteria and bacterial derivatives as drug delivery systems for viral infection
A Faghihkhorasani, HH Ahmed, NM Mashool, M Alwan… - Virology Journal, 2023 - Springer
Viral infections in humans are responsible for fatalities worldwide and contribute to the
incidence of various human ailments. Controllable targeted medicine delivery against many …
incidence of various human ailments. Controllable targeted medicine delivery against many …
[HTML][HTML] Emerging frontiers in drug delivery with special focus on novel techniques for targeted therapies
L Yu, S Liu, S Jia, F Xu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
The management and treatment of disease are achieved via the use of pharmacologically
active substances or drugs. Drugs do not, however, have an intrinsic ability to be effective; …
active substances or drugs. Drugs do not, however, have an intrinsic ability to be effective; …
Phage lysins for intestinal microbiome modulation: current challenges and enabling techniques
The importance of the microbiota in the intestinal tract for human health has been
increasingly recognized. In this perspective, microbiome modulation, a targeted alteration of …
increasingly recognized. In this perspective, microbiome modulation, a targeted alteration of …