We now know that cancer is many different diseases, with great variation even within a
single histological subtype. With the current emphasis on develo** personalized …

The presence, magnitude, and significance of sex differences in the human brain are hotly
debated topics in the scientific community and popular media. This debate is largely fueled …

In vitro production (IVP) of embryos and associated technologies in cattle have shown
significant progress in recent years, in part driven by a better understanding of the full …

The placenta is an ephemeral but critical organ for the survival of all eutherian mammals
and marsupials. It is the primary messenger system between the mother and fetus, where …

It is well understood that sex differences exist between females and males even before they
are born. These sex-dependent differences may contribute to altered growth and …

At fertilization, the gametes endow the embryo with a genomic blueprint, the integrity of
which is affected by the age and environmental exposures of both parents. Recent studies …

Sex differences occur in most non-communicable diseases, including metabolic diseases,
hypertension, cardiovascular disease, psychiatric and neurological disorders and cancer. In …

Genes on the mammalian X chromosome are present in one copy in males and two copies
in females. The complex mechanisms that regulate the X chromosome lead to evolutionary …

Paternal characteristics and exposures influence physiology and disease risks in progeny,
but the mechanisms are mostly unknown. Seminal fluid, which affects female reproductive …

The recent and rapid worldwide increase in non-communicable diseases challenges the
assumption that genetic factors are the primary contributors to such diseases. A new concept …