Green tea catechins (GTC) are polyphenolic compounds present in the unfermented dried
leaves of the plant, Camellia sinensis. Results from a number of randomized, controlled …

Up to 60% of depressed patients do not respond completely to antidepressants (ADs) and
up to 30% do not respond at all. Genetic factors contribute for about 50% of the AD …

Major depressive disorder (MDD) is an emergent cause of personal and socio‐economic
burden, both for the high prevalence of the disorder and the unsatisfying response rate of …

Pharmacotherapy for neuropsychiatric disorders, such as anxiety and depression, has been
characterized by significant inter-individual variability in drug response and the development …

Adverse events, response failures and medication non-compliance are common in patients
receiving medications for the treatment of mental illnesses. A systematic literature review …

In the last decades, the prevalence of obesity has increased globally, reaching epidemic
proportions. 1 Its worldwide prevalence has almost tripled between 1980 and 2016. 2 In the …

Selective serotonin reuptake inhibitors (SSRI s) are first‐line pharmacotherapy for mood and
anxiety disorders. The common mechanism of drugs in this class is antagonism of the …

Obesity is a chronic, multifactorial disease associated with a large number of comorbidities.
The clinical management of obesity involves a stepwise integrated approach, beginning with …

Objective: Major depressive disorder is the most common psychiatric disorder, worldwide,
yet response and remission rates are still unsatisfactory. The identification of genetic …

Background Single nucleotide polymorphism (SNP) variants are abundant, persistent and
widely distributed across the genome and are frequently linked to the development of …