Epigenetics: a catalyst of plant immunity against pathogens

A Hannan Parker, SW Wilkinson, J Ton - New Phytologist, 2022 - Wiley Online Library
The plant immune system protects against pests and diseases. The recognition of stress‐
related molecular patterns triggers localised immune responses, which are often followed by …

A DNA methylation reader complex that enhances gene transcription

CJ Harris, M Scheibe, SP Wongpalee, W Liu… - Science, 2018 - science.org
DNA methylation generally functions as a repressive transcriptional signal, but it is also
known to activate gene expression. In either case, the downstream factors remain largely …

MORC proteins: novel players in plant and animal health

A Koch, HG Kang, J Steinbrenner… - Frontiers in plant …, 2017 - frontiersin.org
Microrchidia (MORC) proteins comprise a family of proteins that have been identified in
prokaryotes and eukaryotes. They are defined by two hallmark domains: a GHKL-type …

Co-targeting RNA polymerases IV and V promotes efficient de novo DNA methylation in Arabidopsis

J Gallego-Bartolomé, W Liu, PH Kuo, S Feng… - Cell, 2019 - cell.com
The RNA-directed DNA methylation (RdDM) pathway in plants controls gene expression via
cytosine DNA methylation. The ability to manipulate RdDM would shed light on the …

A MORC-driven transcriptional switch controls Toxoplasma developmental trajectories and sexual commitment

DC Farhat, C Swale, C Dard, D Cannella, P Ortet… - Nature …, 2020 - nature.com
Toxoplasma gondii has a complex life cycle that is typified by asexual development that
takes place in vertebrates, and sexual reproduction, which occurs exclusively in felids and is …

CRISPR/SpCas9‐mediated double knockout of barley Microrchidia MORC1 and MORC6a reveals their strong involvement in plant immunity, transcriptional gene …

M Galli, E Martiny, J Imani, N Kumar… - Plant Biotechnology …, 2022 - Wiley Online Library
The Microrchidia (MORC) family proteins are important nuclear regulators in both animals
and plants with critical roles in epigenetic gene silencing and genome stabilization. In the …

China's success in increasing per capita food production

J Zhang - Journal of Experimental Botany, 2011 - academic.oup.com
China has to feed 20% of the global population with only about 5% of the planet's water
resources and 7% of its arable land. With such limited natural conditions, however, China's …

Arabidopsis MORC proteins function in the efficient establishment of RNA directed DNA methylation

Y Xue, Z Zhong, CJ Harris, J Gallego-Bartolomé… - Nature …, 2021 - nature.com
The Microrchidia (MORC) family of ATPases are required for transposable element (TE)
silencing and heterochromatin condensation in plants and animals, and C. elegans MORC …

Single-nucleus RNA-seq reveals that MBD5, MBD6, and SILENZIO maintain silencing in the vegetative cell of develo** pollen

L Ichino, CL Picard, J Yun, M Chotai, S Wang, EK Lin… - Cell reports, 2022 - cell.com
Silencing of transposable elements (TEs) drives the evolution of numerous redundant
mechanisms of transcriptional regulation. Arabidopsis MBD5, MBD6, and SILENZIO act as …

Further analysis of barley MORC 1 using a highly efficient RNA‐guided Cas9 gene‐editing system

N Kumar, M Galli, J Ordon, J Stuttmann… - Plant Biotechnology …, 2018 - Wiley Online Library
Microrchidia (MORC) proteins comprise a family of proteins that have been identified in
prokaryotes and eukaryotes. They are defined by two hallmark domains: a GHKL‐type ATP …