Pericyte dynamics during angiogenesis: new insights from new identities

PC Stapor, RS Sweat, DC Dashti… - Journal of vascular …, 2014 - karger.com
Therapies aimed at manipulating the microcirculation require the ability to control
angiogenesis, defined as the sprouting of new capillaries from existing vessels. Blocking …

Understanding angiogenesis during aging: opportunities for discoveries and new models

NA Hodges, AD Suarez-Martinez… - Journal of applied …, 2018 - journals.physiology.org
Microvascular network growth and remodeling are common denominators for most age-
related pathologies. For multiple pathologies (myocardial infarction, stroke, hypertension) …

Vascular endothelial growth factor coordinates islet innervation via vascular scaffolding

RB Reinert, Q Cai, JY Hong, JL Plank… - …, 2014 - journals.biologists.com
Neurovascular alignment is a common anatomical feature of organs, but the mechanisms
leading to this arrangement are incompletely understood. Here, we show that vascular …

An angiogenesis model for investigating multicellular interactions across intact microvascular networks

PC Stapor, MS Azimi, T Ahsan… - American Journal of …, 2013 - journals.physiology.org
Develo** therapies aimed at manipulating microvascular remodeling requires a better
understanding of angiogenesis and how angiogenesis relates to other network remodeling …

VEGF‐C induces lymphangiogenesis and angiogenesis in the rat mesentery culture model

RS Sweat, DC Sloas, WL Murfee - Microcirculation, 2014 - Wiley Online Library
Objective Lymphatic and blood microvascular systems are critical for tissue function. Insights
into the coordination of both systems can be gained by investigating the relationships …

Relationships between lymphangiogenesis and angiogenesis during inflammation in rat mesentery microvascular networks

RS Sweat, PC Stapor, WL Murfee - Lymphatic research and biology, 2012 - liebertpub.com
Background: Lymphatic and blood microvascular systems play a coordinated role in the
regulation of interstitial fluid balance and immune cell trafficking during inflammation. The …

An Ex Vivo Model for Anti-Angiogenic Drug Testing on Intact Microvascular Networks

MS Azimi, L Myers, M Lacey, SA Stewart, Q Shi… - PLoS …, 2015 - journals.plos.org
New models of angiogenesis that mimic the complexity of real microvascular networks are
needed. Recently, our laboratory demonstrated that cultured rat mesentery tissues contain …

Aging is associated with impaired angiogenesis, but normal microvascular network structure, in the rat mesentery

RS Sweat, DC Sloas, SA Stewart… - American Journal …, 2017 - journals.physiology.org
A big problem associated with aging is thought to be impaired microvascular growth or
angiogenesis. However, to link the evidence for impaired angiogenesis to microvascular …

Induction of microvascular network growth in the mouse mesentery

AD Suarez‐Martinez, SM Peirce, BE Isakson… - …, 2018 - Wiley Online Library
Objective Motivated by observations of mesenteries harvested from mice treated with
tamoxifen dissolved in oil for inducible gene mutation studies, the objective of this study was …

The maintenance of adult peripheral adult nerve and microvascular networks in the rat mesentery culture model

NA Hodges, RW Barr, WL Murfee - Journal of neuroscience methods, 2020 - Elsevier
Background Neurovascular patterning is an emerging area of microvascular research. While
overlap** molecular signals highlight links between angiogenesis and neurogenesis …