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Cytokines: from clinical significance to quantification
Cytokines are critical mediators that oversee and regulate immune and inflammatory
responses via complex networks and serve as biomarkers for many diseases. Quantification …
responses via complex networks and serve as biomarkers for many diseases. Quantification …
Using single-vesicle technologies to unravel the heterogeneity of extracellular vesicles
Extracellular vesicles (EVs) are heterogeneous lipid containers with a complex molecular
cargo comprising several populations with unique roles in biological processes. These …
cargo comprising several populations with unique roles in biological processes. These …
Roadmap on label‐free super‐resolution imaging
Label‐free super‐resolution (LFSR) imaging relies on light‐scattering processes in
nanoscale objects without a need for fluorescent (FL) staining required in super‐resolved FL …
nanoscale objects without a need for fluorescent (FL) staining required in super‐resolved FL …
Characterizing extracellular vesicles and their diverse RNA contents
Cells release nanometer-scale, lipid bilayer-enclosed biomolecular packages (extracellular
vesicles; EVs) into their surrounding environment. EVs are hypothesized to be intercellular …
vesicles; EVs) into their surrounding environment. EVs are hypothesized to be intercellular …
Tetraspanins are unevenly distributed across single extracellular vesicles and bias sensitivity to multiplexed cancer biomarkers
Background Tetraspanin expression of extracellular vesicles (EVs) is often used as a
surrogate for their detection and classification, a practice that typically assumes their …
surrogate for their detection and classification, a practice that typically assumes their …
Scattering-based light microscopy: from metal nanoparticles to single proteins
L Priest, JS Peters, P Kukura - Chemical reviews, 2021 - ACS Publications
Our ability to detect, image, and quantify nanoscopic objects and molecules with visible light
has undergone dramatic improvements over the past few decades. While fluorescence has …
has undergone dramatic improvements over the past few decades. While fluorescence has …
Bond-selective imaging by optically sensing the mid-infrared photothermal effect
Mid-infrared (IR) spectroscopic imaging using inherent vibrational contrast has been broadly
used as a powerful analytical tool for sample identification and characterization. However …
used as a powerful analytical tool for sample identification and characterization. However …
Elucidating methods for isolation and quantification of exosomes: a review
Exosomes are the smallest extracellular vesicles present in most of the biological fluids.
They are found to play an important role in cell signaling, immune response, tumor …
They are found to play an important role in cell signaling, immune response, tumor …
Separation, characterization, and standardization of extracellular vesicles for drug delivery applications
Extracellular vesicles (EVs) are membranous nanovesicles secreted from living cells,
shuttling macromolecules in intercellular communication and potentially possessing intrinsic …
shuttling macromolecules in intercellular communication and potentially possessing intrinsic …
Understanding exosomes: Part 1—Characterization, quantification and isolation techniques
RJ Miron, Y Zhang - Periodontology 2000, 2024 - Wiley Online Library
Exosomes are the smallest subset of extracellular signaling vesicles secreted by most cells
with a diameter in the range of 30–150 nm. Their use has gained great momentum recently …
with a diameter in the range of 30–150 nm. Their use has gained great momentum recently …