Brown and beige adipose tissue: a novel therapeutic strategy for obesity and type 2 diabetes mellitus
L Cheng, J Wang, H Dai, Y Duan, Y An, L Shi, Y Lv… - Adipocyte, 2021 - Taylor & Francis
Mammalian adipose tissue can be divided into two major types, namely, white adipose
tissue (WAT) and brown adipose tissue (BAT). According to classical view, the main function …
tissue (WAT) and brown adipose tissue (BAT). According to classical view, the main function …
Recent update on the molecular mechanisms of gonadal steroids action in adipose tissue
A Wawrzkiewicz-Jałowiecka, A Lalik… - International Journal of …, 2021 - mdpi.com
The gonadal steroids, including androgens, estrogens and progestogens, are involved in
the control of body fat distribution in humans. Nevertheless, not only the size and localization …
the control of body fat distribution in humans. Nevertheless, not only the size and localization …
Hypoglycemic effect of the polysaccharides from Astragalus membranaceus on type 2 diabetic mice based on the “gut microbiota–mucosal barrier”
X Chen, C Chen, X Fu - Food & Function, 2022 - pubs.rsc.org
Astragalus membranaceus polysaccharides (APP), the main active constituent, possess
numerous bioactivities. In this research, a type 2 diabetes mellitus (T2DM) mouse model …
numerous bioactivities. In this research, a type 2 diabetes mellitus (T2DM) mouse model …
[HTML][HTML] Role of bile acid receptor FXR in development and function of brown adipose tissue
J Yang, HD de Vries, A Mayeuf-Louchart… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Bile acids act as signalling molecules that contribute to maintenance of energy homeostasis
in mice and humans. Activation of G-protein-coupled bile acid receptor TGR5 induces …
in mice and humans. Activation of G-protein-coupled bile acid receptor TGR5 induces …
[HTML][HTML] Adipose Tissue Plasticity: A Comprehensive Definition and Multidimensional Insight
YY Mo, YX Han, SN Xu, HL Jiang, HX Wu, JM Cai, L Li… - Biomolecules, 2024 - mdpi.com
Adipose tissue is composed of adipocytes, stromal vascular fraction, nerves, surrounding
immune cells, and the extracellular matrix. Under various physiological or pathological …
immune cells, and the extracellular matrix. Under various physiological or pathological …
Co-treatment with miR-21-5p inhibitor and Aurora kinase inhibitor reversine suppresses breast cancer progression by targeting sprouty RTK signaling antagonist 2
Y Zhang, Y Wang, J Xue, W Liang, Z Zhang… - …, 2022 - Taylor & Francis
Numerous studies have reported the regulatory effects of miR-21-5p and reversine in human
breast cancer (HBC). However, the mechanism of reversine and miR-21-5p has not been …
breast cancer (HBC). However, the mechanism of reversine and miR-21-5p has not been …
MicroRNAs as mediators of adipose thermogenesis and potential therapeutic targets for obesity
Simple Summary Thermogenesis in beige and brown adipose tissue has a significant role in
combating metabolic disorders, such as type 2 diabetes and diet-induced obesity. A large …
combating metabolic disorders, such as type 2 diabetes and diet-induced obesity. A large …
The Effects of DDI1 on Inducing Differentiation in Ovine Preadipocytes via Oar-miR-432
M **, Z Yuan, T Li, H Wang, C Wei - International Journal of Molecular …, 2023 - mdpi.com
Reducing fat deposition in sheep (Ovis aries) tails is one of the most important ways to
combat rising costs and control consumer preference. Our previous studies have shown that …
combat rising costs and control consumer preference. Our previous studies have shown that …
Develo** miR‐133a Zipper Nanoparticles for Targeted Enhancement of Thermogenic Adipocyte Generation
Existing delivery methods for RNAi therapeutics encounter challenges, including stability,
specificity, and off‐target effects, which restrict their clinical effectiveness. In this study, we …
specificity, and off‐target effects, which restrict their clinical effectiveness. In this study, we …
Zinc improves semen parameters in high-fat diet-induced male rats by regulating the expression of LncRNA in testis tissue
J Ma, J Bi, B Sun, H Li, Y Li, S Wang - Biological trace element research, 2023 - Springer
This study aimed to identify differentially expressed LncRNAs in testis tissue of male rats
induced by high-fat diet and their changes after zinc supplementation, by constructing a high …
induced by high-fat diet and their changes after zinc supplementation, by constructing a high …