The role of oxidative stress, antioxidants and vascular inflammation in cardiovascular disease (a review)

HN Siti, Y Kamisah, J Kamsiah - Vascular pharmacology, 2015 - Elsevier
The concept of mild chronic vascular inflammation as part of the pathophysiology of
cardiovascular disease, most importantly hypertension and atherosclerosis, has been well …

Reactive oxygen species: a key hallmark of cardiovascular disease

N Panth, KR Paudel, K Parajuli - Advances in medicine, 2016 - Wiley Online Library
Cardiovascular diseases (CVDs) have been the prime cause of mortality worldwide for
decades. However, the underlying mechanism of their pathogenesis is not fully clear yet. It …

Reactive oxygen species: key regulators in vascular health and diseases

Q Chen, Q Wang, J Zhu, Q **ao… - British journal of …, 2018 - Wiley Online Library
ROS are a group of small reactive molecules that play critical roles in the regulation of
various cell functions and biological processes. In the vascular system, physiological levels …

Vitamin C and cardiovascular disease: an update

MB Morelli, J Gambardella, V Castellanos, V Trimarco… - Antioxidants, 2020 - mdpi.com
The potential beneficial effects of the antioxidant properties of vitamin C have been
investigated in a number of pathological conditions. In this review, we assess both clinical …

Sympathetic regulation of vascular function in health and disease

RM Bruno, L Ghiadoni, G Seravalle, R Dell'Oro… - Frontiers in …, 2012 - frontiersin.org
The sympathetic nervous system (SNS) is known to play a pivotal role in short-and long-term
regulation of different functions of the cardiovascular system. In the past decades increasing …

[HTML][HTML] Oxidative stress and inflammation contribute to traffic noise-induced vascular and cerebral dysfunction via uncoupling of nitric oxide synthases

A Daiber, S Kröller-Schön, M Oelze, O Hahad, H Li… - Redox biology, 2020 - Elsevier
Environmental pollution and non-chemical stressors such as mental stress or traffic noise
exposure are increasingly accepted as health risk factors with substantial contribution to …

Sympathetic overactivity in chronic kidney disease: consequences and mechanisms

J Kaur, BE Young, PJ Fadel - International journal of molecular sciences, 2017 - mdpi.com
The incidence of chronic kidney disease (CKD) is increasing worldwide, with more than 26
million people suffering from CKD in the United States alone. More patients with CKD die of …

Oxidative stress in chronic vascular disease: from prediction to prevention

F Santilli, D D'Ardes, G Davi - Vascular pharmacology, 2015 - Elsevier
This review article is intended to describe the strong relationship between oxidative stress
and vascular disease. Reactive oxygen species (ROS) play an important role in the …

Effects of vitamin C supplementation on essential hypertension: A systematic review and meta-analysis

Y Guan, P Dai, H Wang - Medicine, 2020 - journals.lww.com
Background: Vitamin C as a supplement to treat hypertension has been proposed. However,
it remains controversial whether vitamin C can improve blood pressure in patients with …

Cardiac dysfunction and oxidative stress in the metabolic syndrome: an update on antioxidant therapies

O Ilkun, S Boudina - Current pharmaceutical design, 2013 - ingentaconnect.com
The metabolic syndrome (MetS) is a cluster of risk factors including obesity, insulin
resistance, dyslipidemia, elevated blood pressure and glucose intolerance. The MetS …