The market of chiral drugs: Chiral switches versus de novo enantiomerically pure compounds

A Calcaterra, I D'Acquarica - Journal of pharmaceutical and biomedical …, 2018 - Elsevier
This review article is aimed at providing an overview of the current market of chiral drugs by
exploring which is the nowadays tendency, for the pharmaceutical industry, either to exploit …

Recent progress in the development of chiral stationary phases for high‐performance liquid chromatography

JH Zhang, SM **e, LM Yuan - Journal of separation science, 2022 - Wiley Online Library
Separations and analyses of chiral compounds are important in many fields, including
pharmaceutical production, preparation of chemical intermediates, and biochemistry. High …

Current and future trends in UHPLC

S Fekete, J Schappler, JL Veuthey… - TrAC Trends in Analytical …, 2014 - Elsevier
Since its commercial introduction in 2004, there has been a considerable interest in ultra-
high-performance (pressure) liquid chromatography (UHPLC), which dramatically increases …

Recent applications in chiral high performance liquid chromatography: a review

A Cavazzini, L Pasti, A Massi, N Marchetti… - Analytica Chimica Acta, 2011 - Elsevier
The most important and broadly used chiral stationary phases (CSPs) for high performance
liquid chromatography (HPLC) are reviewed. After a short description of the state of the art …

Advances in high-throughput and high-efficiency chiral liquid chromatographic separations

DC Patel, MF Wahab, DW Armstrong… - … of Chromatography a, 2016 - Elsevier
The need for improved liquid chromatographic chiral separations has led to the
advancement of chiral screening techniques as well as the development of new, high …

Gone in seconds: praxis, performance, and peculiarities of ultrafast chiral liquid chromatography with superficially porous particles

DC Patel, ZS Breitbach, MF Wahab… - Analytical …, 2015 - ACS Publications
A variety of brush-type chiral stationary phases (CSPs) were developed using superficially
porous particles (SPPs). Given their high efficiencies and relatively low back pressures …

Enantioselective high-performance liquid chromatographic separations to study occurrence and fate of chiral pesticides in soil, water, and agricultural products

E Lucci, C Dal Bosco, L Antonelli, C Fanali… - … of Chromatography A, 2022 - Elsevier
As many as 40% of all plant protection products currently used contain chiral active
ingredients. Enantiomers of the same pesticide have identical physicochemical properties in …

[HTML][HTML] Noncovalent complexes of cyclodextrin with small organic molecules: Applications and insights into host–guest interactions in the gas phase and condensed …

J Lee, SS Lee, S Lee, HB Oh - Molecules, 2020 - mdpi.com
Cyclodextrins (CDs) have drawn a lot of attention from the scientific communities as a model
system for host–guest chemistry and also due to its variety of applications in the …

Potency testing of cannabinoids by liquid and supercritical fluid chromatography: Where we are, what we need

S Felletti, C De Luca, A Buratti, D Bozza… - … of Chromatography A, 2021 - Elsevier
Hemp and cannabis industry is undergoing a renewed interest due to legalization of
marijuana (a topic that all countries are discussing, especially in recent years) and the …

Chiral separations in food analysis

G D'Orazio, C Fanali, M Asensio-Ramos… - TrAC Trends in Analytical …, 2017 - Elsevier
The determination of enantiomers is a very important topic in different areas including
pharmaceutical, biomedical, agrochemical and food fields. In fact these compounds possess …