Background Cancer is the most prevalent cause of death globally, and radiotherapy is
considered the standard of care for most solid tumors, including lung, breast, esophageal …

Intercellular communication is a critical process that ensures cooperation between distinct
cell types and maintains homeostasis. EVs, which were initially described as cellular debris …

The microbiota is composed of commensal bacteria and other microorganisms that live on
the epithelial barriers of the host. The commensal microbiota is important for the health and …

Extracellular vesicles (EVs) are minute vesicles with lipid bilayer membranes. EVs are
secreted by cells for intercellular communication. Recently, EVs have received much …

The tumor immune microenvironment is a determinant of response to cancer
immunotherapy and, in many cases, is prognostic for patient survival independently of the …

Purpose Reactive oxygen species (ROS) are produced in cancer cells as a result of
increased metabolic rate, dysfunction of mitochondria, elevated cell signaling, expression of …

Background The pathogenesis of colorectal cancer recurrence after a curative resection
remains poorly understood. A yet-to-be accounted for variable is the composition and …

In cancer treatment, traditional radiotherapy (RT) is routinely conducted in local tumors and
limited by radioresistance, while recently emerged immunotherapy is confronted with low …

Tumor cells secrete extracellular vesicles (EVs) for intercellular communication. EVs by
transporting different proteins, nucleic acids, and lipids contribute to affect target cell function …

Exosomes are nanometer-sized extracellular vesicles that are believed to function as
intercellular communicators. Here, we report that exosomes are able to modify the radiation …