Metabolic engineering strategies to enable microbial utilization of C1 feedstocks
Abstract One-carbon (C1) substrates are preferred feedstocks for the biomanufacturing
industry and have recently gained attention owing to their natural abundance, low …
industry and have recently gained attention owing to their natural abundance, low …
Heme oxygenase-1 signaling and redox homeostasis in physiopathological conditions
Heme-oxygenase is the enzyme responsible for degradation of endogenous iron
protoporphyirin heme; it catalyzes the reaction's rate-limiting step, resulting in the release of …
protoporphyirin heme; it catalyzes the reaction's rate-limiting step, resulting in the release of …
Mitochondria and endothelial function
MA Kluge, JL Fetterman, JA Vita - Circulation research, 2013 - Am Heart Assoc
In contrast to their role in cell types with higher energy demands, mitochondria in endothelial
cells primarily function in signaling cellular responses to environmental cues. This article …
cells primarily function in signaling cellular responses to environmental cues. This article …
Carbon monoxide–physiology, detection and controlled release
SH Heinemann, T Hoshi, M Westerhausen… - Chemical …, 2014 - pubs.rsc.org
Carbon monoxide (CO) is increasingly recognized as a cell-signalling molecule akin to nitric
oxide (NO). CO has attracted particular attention as a potential therapeutic agent because of …
oxide (NO). CO has attracted particular attention as a potential therapeutic agent because of …
Carbon monoxide poisoning
LK Weaver - New England Journal of Medicine, 2009 - Mass Medical Soc
A 39-year-old female executive has a several-month history of fatigue, headache, and
memory lapse. During a period of feeling worse than usual, she called a friend, who arrived …
memory lapse. During a period of feeling worse than usual, she called a friend, who arrived …
Plight of CORMs: The unreliability of four commercially available CO-releasing molecules, CORM-2, CORM-3, CORM-A1, and CORM-401, in studying CO biology
Carbon monoxide (CO) is an endogenously produced gaseous signaling molecule with
demonstrated pharmacological effects. In studying CO biology, three delivery forms have …
demonstrated pharmacological effects. In studying CO biology, three delivery forms have …
A new era of cancer phototherapy: mechanisms and applications
Y Wang, K Ma, M Kang, D Yan, N Niu, S Yan… - Chemical Society …, 2024 - pubs.rsc.org
The past decades have witnessed great strides in phototherapy as an experimental option
or regulation-approved treatment in numerous cancer indications. Of particular interest is …
or regulation-approved treatment in numerous cancer indications. Of particular interest is …
Smoking-induced skeletal muscle dysfunction. From evidence to mechanisms
H Degens, G Gayan-Ramirez… - American journal of …, 2015 - atsjournals.org
Smoking is the most important risk factor for the development of chronic obstructive
pulmonary disease (COPD). Patients with COPD commonly suffer from skeletal muscle …
pulmonary disease (COPD). Patients with COPD commonly suffer from skeletal muscle …
The health effects of exercising in air pollution
The health benefits of exercise are well known. Many of the most accessible forms of
exercise, such as walking, cycling, and running often occur outdoors. This means that …
exercise, such as walking, cycling, and running often occur outdoors. This means that …
Myocardial injury and long-term mortality following moderate to severe carbon monoxide poisoning
CR Henry, D Satran, B Lindgren, C Adkinson… - Jama, 2006 - jamanetwork.com
ContextCarbon monoxide (CO) poisoning is a common cause of toxicological morbidity and
mortality. Myocardial injury is a frequent consequence of moderate to severe CO poisoning …
mortality. Myocardial injury is a frequent consequence of moderate to severe CO poisoning …