Metabolic engineering strategies to enable microbial utilization of C1 feedstocks

W Jiang, D Hernández Villamor, H Peng… - Nature Chemical …, 2021 - nature.com
Abstract One-carbon (C1) substrates are preferred feedstocks for the biomanufacturing
industry and have recently gained attention owing to their natural abundance, low …

Heme oxygenase-1 signaling and redox homeostasis in physiopathological conditions

V Consoli, V Sorrenti, S Grosso, L Vanella - Biomolecules, 2021 - mdpi.com
Heme-oxygenase is the enzyme responsible for degradation of endogenous iron
protoporphyirin heme; it catalyzes the reaction's rate-limiting step, resulting in the release of …

Mitochondria and endothelial function

MA Kluge, JL Fetterman, JA Vita - Circulation research, 2013 - Am Heart Assoc
In contrast to their role in cell types with higher energy demands, mitochondria in endothelial
cells primarily function in signaling cellular responses to environmental cues. This article …

Carbon monoxide–physiology, detection and controlled release

SH Heinemann, T Hoshi, M Westerhausen… - Chemical …, 2014 - pubs.rsc.org
Carbon monoxide (CO) is increasingly recognized as a cell-signalling molecule akin to nitric
oxide (NO). CO has attracted particular attention as a potential therapeutic agent because of …

Carbon monoxide poisoning

LK Weaver - New England Journal of Medicine, 2009 - Mass Medical Soc
A 39-year-old female executive has a several-month history of fatigue, headache, and
memory lapse. During a period of feeling worse than usual, she called a friend, who arrived …

Plight of CORMs: The unreliability of four commercially available CO-releasing molecules, CORM-2, CORM-3, CORM-A1, and CORM-401, in studying CO biology

N Bauer, Z Yuan, X Yang, B Wang - Biochemical Pharmacology, 2023 - Elsevier
Carbon monoxide (CO) is an endogenously produced gaseous signaling molecule with
demonstrated pharmacological effects. In studying CO biology, three delivery forms have …

A new era of cancer phototherapy: mechanisms and applications

Y Wang, K Ma, M Kang, D Yan, N Niu, S Yan… - Chemical Society …, 2024 - pubs.rsc.org
The past decades have witnessed great strides in phototherapy as an experimental option
or regulation-approved treatment in numerous cancer indications. Of particular interest is …

Smoking-induced skeletal muscle dysfunction. From evidence to mechanisms

H Degens, G Gayan-Ramirez… - American journal of …, 2015 - atsjournals.org
Smoking is the most important risk factor for the development of chronic obstructive
pulmonary disease (COPD). Patients with COPD commonly suffer from skeletal muscle …

The health effects of exercising in air pollution

LV Giles, MS Koehle - Sports Medicine, 2014 - Springer
The health benefits of exercise are well known. Many of the most accessible forms of
exercise, such as walking, cycling, and running often occur outdoors. This means that …

Myocardial injury and long-term mortality following moderate to severe carbon monoxide poisoning

CR Henry, D Satran, B Lindgren, C Adkinson… - Jama, 2006 - jamanetwork.com
ContextCarbon monoxide (CO) poisoning is a common cause of toxicological morbidity and
mortality. Myocardial injury is a frequent consequence of moderate to severe CO poisoning …