Advances in nanomaterials for photodynamic therapy applications: Status and challenges

J Chen, T Fan, Z **e, Q Zeng, P Xue, T Zheng, Y Chen… - Biomaterials, 2020 - Elsevier
Photodynamic therapy (PDT), as a non-invasive therapeutic modality that is alternative to
radiotherapy and chemotherapy, is extensively investigated for cancer treatments. Although …

Reactive oxygen species (ROS)-based nanomedicine

B Yang, Y Chen, J Shi - Chemical reviews, 2019 - ACS Publications
Reactive oxygen species (ROS) play an essential role in regulating various physiological
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …

Supramolecular photosensitizer enables oxygen-independent generation of hydroxyl radicals for photodynamic therapy

KX Teng, LY Niu, QZ Yang - Journal of the American Chemical …, 2023 - ACS Publications
The highly oxygen-dependent nature of photodynamic therapy (PDT) limits its therapeutic
efficacy against hypoxic solid tumors in clinics, which is an urgent problem to be solved …

Glucose oxidase‐instructed multimodal synergistic cancer therapy

LH Fu, C Qi, YR Hu, J Lin, P Huang - Advanced Materials, 2019 - Wiley Online Library
Over the past 3 years, glucose oxidase (GOx) has aroused great research interest in the
context of cancer treatment due to its inherent biocompatibility and biodegradability, and its …

Reactive oxygen species‐regulating strategies based on nanomaterials for disease treatment

C Zhang, X Wang, J Du, Z Gu, Y Zhao - Advanced Science, 2021 - Wiley Online Library
Reactive oxygen species (ROS) play an essential role in physiological and pathological
processes. Studies on the regulation of ROS for disease treatments have caused wide …

Recent advances in photo‐responsive carbon dots for tumor therapy

H Zhang, Y Liu, S Qu - Responsive Materials, 2024 - Wiley Online Library
The precision treatment of tumors with minimal side effects is associated with improved
human health and quality of life. In recent years, phototherapy has attracted significant …

An Adenosine Triphosphate-Responsive Autocatalytic Fenton Nanoparticle for Tumor Ablation with Self-Supplied H2O2 and Acceleration of Fe(III)/Fe(II) Conversion

L Zhang, SS Wan, CX Li, L Xu, H Cheng, XZ Zhang - Nano letters, 2018 - ACS Publications
Chemodynamic therapy (CDT) can efficiently destroy tumor cells via Fenton reaction in the
presence of H2O2 and a robust catalyst. However, it has faced severe challenges including …

Molecular and nanoengineering approaches towards activatable cancer immunotherapy

C Zhang, K Pu - Chemical Society Reviews, 2020 - pubs.rsc.org
Cancer immunotherapy is an emerging treatment strategy that modulates the immune
system to fight against cancer. Although several immunotherapeutic agents have been …

Nanoenzyme-augmented cancer sonodynamic therapy by catalytic tumor oxygenation

P Zhu, Y Chen, J Shi - ACS nano, 2018 - ACS Publications
Ultrasound (US)-triggered sonodynamic therapy (SDT) can solve the critical issue of low
tissue-penetrating depth of traditional phototriggered therapies, but the SDT efficacy is still …

Versatile types of organic/inorganic nanohybrids: from strategic design to biomedical applications

N Zhao, L Yan, X Zhao, X Chen, A Li, D Zheng… - Chemical …, 2018 - ACS Publications
Organic/inorganic nanohybrids have attracted widespread interests due to their favorable
properties and promising applications in biomedical areas. Great efforts have been made to …