Spatial organization is a hallmark of all living systems. Even bacteria, the smallest forms of
cellular life, display defined shapes and complex internal organization, showcasing a highly …

Model bacteria, such as E. coli and B. subtilis, tightly regulate cell cycle progression to
achieve consistent cell size distributions and replication dynamics. Many of the hallmark …

In model bacteria, such as E. coli and B. subtilis, regulation of cell-cycle progression and
cellular organization achieves consistency in cell size, replication dynamics, and …

Many bacteria switch between a sessile and a motile mode in response to environmental
and host-related signals. Porphyromonas gingivalis, an oral anaerobe implicated in the …

In bacteria, chromosomal DNA must be efficiently compacted to fit inside the small cell
compartment while remaining available for the proteins involved in replication, segregation …

Mycobacterial cellular variations in growth and division increase heterogeneity in cell length,
possibly contributing to cell-to-cell variation in host and antibiotic stress tolerance. This may …

Nucleoid-associated proteins (NAPs) are responsible for maintaining highly organized and
yet dynamic chromosome structure in bacteria. The genus Mycobacterium possesses a …

Bacterial chromosomes have a single, unique replication origin (named oriC), from which
DNA synthesis starts. This study describes methods of visualizing oriC regions and the …

Spreading resistance to antibiotics and the emergence of multidrug-resistant strains have
become frequent in many bacterial species, including mycobacteria, which are the causative …

The mycobacterial cell envelope is a complex multilayered structure that provides the
strength to the rod-shaped cell and creates the permeability barrier against antibiotics and …