MicroRNAs: roles in cardiovascular development and disease

S Kalayinia, F Arjmand, M Maleki, M Malakootian… - Cardiovascular …, 2021 - Elsevier
Cardiovascular diseases (CVDs) comprise a group of disorders ranging from peripheral
artery, coronary artery, cardiac valve, cardiac muscle, and congenital heart diseases to …

The emerging role of MicroRNAs in bone diseases and their therapeutic potential

LA Bravo Vázquez, MY Moreno Becerril… - Molecules, 2021 - mdpi.com
MicroRNAs (miRNAs) are a class of small (20–24 nucleotides), highly conserved, non-
coding RNA molecules whose main function is the post-transcriptional regulation of gene …

Integrated transcriptome and microRNA analysis reveals molecular responses to high-temperature stress in the liver of American shad (Alosa sapidissima)

Y Liu, Z Liang, Y Li, W Zhu, B Feng, W Xu, J Fu, P Wei… - BMC genomics, 2024 - Springer
Background Fish reproduction, development and growth are directly affected by
temperature, investigating the regulatory mechanisms behind high temperature stress is …

Crafting a blueprint for MicroRNA in cardiovascular diseases (CVDs)

SU Khan, S Saeed, AN Sheikh, FM Arbi… - Current Problems in …, 2023 - Elsevier
Cardiovascular diseases (CVDs) encompass a range of disorders, from congenital heart
malformation, cardiac valve, peripheral artery, coronary artery, cardiac muscle diseases, and …

[HTML][HTML] Layered double hydroxide as a potent non-viral vector for nucleic acid delivery using gene-activated scaffolds for tissue regeneration applications

LS Costard, DC Kelly, RN Power, C Hobbs… - Pharmaceutics, 2020 - mdpi.com
Nonviral vectors offer a safe alternative to viral vectors for gene therapy applications, albeit
typically exhibiting lower transfection efficiencies. As a result, there remains a significant …

PiRNA in cardiovascular disease: focus on cardiac remodeling and cardiac protection

K Zhang, Y Li, Y Huang, K Sun - Journal of Cardiovascular Translational …, 2023 - Springer
Cardiovascular diseases (CVDs) are common causes of death, which take about 18.6
million lives worldwide every year. Currently, exploring strategies that delay ventricular …

Downregulation of miR-181a-5p alleviates oxidative stress and inflammation in coronary microembolization-induced myocardial damage by directly targeting XIAP

Z You, L Man-Yun, C Zhi-Qing… - Journal of Geriatric …, 2021 - pmc.ncbi.nlm.nih.gov
BACKGROUND Coronary microembolization (CME) is a complicated problem that
commonly arises in the context of coronary angioplasty. MicroRNAs play crucial roles in …

Cardiovascular Disease and MiRNAs: Possible Oxidative Stress-Regulating Roles of MiRNAs

S Lee - Antioxidants, 2024 - mdpi.com
MicroRNAs (miRNAs) have been highlighted as key players in numerous diseases, and
accumulating evidence indicates that pathological expressions of miRNAs contribute to both …

MicroRNAs in chronic pediatric diseases

M Zhang, Y Han - Experimental and Therapeutic …, 2024 - spandidos-publications.com
MicroRNAs are small non-coding RNAs with a length of 20-24 nucleotides. They bind to the
3'-untranslated region of target genes to induce the degradation of target mRNAs or inhibit …

Downregulation of Talin‐1 is associated with the increased expression of miR‐182‐5p and miR‐9‐5p in coronary artery disease

A Gholipour, F Shakerian, A Zahedmehr… - Journal of clinical …, 2022 - Wiley Online Library
Background Evidence indicates that the dysregulation of extracellular matrix (ECM)
components can lead to cardiovascular diseases. The Talin‐1 (TLN1) gene is a major …