Guiding questions to avoid data leakage in biological machine learning applications

J Bernett, DB Blumenthal, DG Grimm, F Haselbeck… - Nature …, 2024‏ - nature.com
Abstract Machine learning methods for extracting patterns from high-dimensional data are
very important in the biological sciences. However, in certain cases, real-world applications …

Artificial intelligence in the risk prediction models of cardiovascular disease and development of an independent validation screening tool: a systematic review

Y Cai, YQ Cai, LY Tang, YH Wang, M Gong, TC **g… - BMC medicine, 2024‏ - Springer
Background A comprehensive overview of artificial intelligence (AI) for cardiovascular
disease (CVD) prediction and a screening tool of AI models (AI-Ms) for independent external …

[HTML][HTML] Consolidated reporting guidelines for prognostic and diagnostic machine learning modeling studies: development and validation

W Klement, K El Emam - Journal of Medical Internet Research, 2023‏ - jmir.org
Background The reporting of machine learning (ML) prognostic and diagnostic modeling
studies is often inadequate, making it difficult to understand and replicate such studies. To …

Computational models for clinical applications in personalized medicine—guidelines and recommendations for data integration and model validation

CB Collin, T Gebhardt, M Golebiewski… - Journal of personalized …, 2022‏ - mdpi.com
The future development of personalized medicine depends on a vast exchange of data from
different sources, as well as harmonized integrative analysis of large-scale clinical health …

[HTML][HTML] Pitfalls in develo** machine learning models for predicting cardiovascular diseases: challenge and solutions

YQ Cai, DX Gong, LY Tang, Y Cai, HJ Li… - Journal of Medical …, 2024‏ - jmir.org
In recent years, there has been explosive development in artificial intelligence (AI), which
has been widely applied in the health care field. As a typical AI technology, machine …

Spatial machine learning: new opportunities for regional science

K Kopczewska - The Annals of Regional Science, 2022‏ - Springer
This paper is a methodological guide to using machine learning in the spatial context. It
provides an overview of the existing spatial toolbox proposed in the literature: unsupervised …

Cracking the black box of deep sequence-based protein–protein interaction prediction

J Bernett, DB Blumenthal, M List - Briefings in Bioinformatics, 2024‏ - academic.oup.com
Identifying protein–protein interactions (PPIs) is crucial for deciphering biological pathways.
Numerous prediction methods have been developed as cheap alternatives to biological …

The role of artificial intelligence in radiotherapy clinical practice

G Landry, C Kurz, A Traverso - BJR| Open, 2023‏ - academic.oup.com
This review article visits the current state of artificial intelligence (AI) in radiotherapy clinical
practice. We will discuss how AI has a place in the modern radiotherapy workflow at the …

Radiomics and dosiomics signature from whole lung predicts radiation pneumonitis: A model development study with prospective external validation and decision …

Z Zhang, Z Wang, M Yan, J Yu, A Dekker, L Zhao… - International Journal of …, 2023‏ - Elsevier
Purpose Radiation pneumonitis (RP) is one of the common side effects of radiation therapy
in the thoracic region. Radiomics and dosiomics quantify information implicit within medical …

Determining asthma endotypes and outcomes: Complementing existing clinical practice with modern machine learning

A Ray, J Das, SE Wenzel - Cell Reports Medicine, 2022‏ - cell.com
There is unprecedented opportunity to use machine learning to integrate high-dimensional
molecular data with clinical characteristics to accurately diagnose and manage disease …