Proposed genetic approaches for reducing human malaria include population modification,
which introduces genes into vector mosquitoes to reduce or prevent parasite transmission …

The last century has witnessed the introduction, establishment and expansion of mosquito-
borne diseases into diverse new geographic ranges. Malaria is transmitted by female …

Gene drive-modified mosquitoes (GDMMs) are proposed as new tools for control and
elimination of malaria and other mosquito-borne diseases, and promising results have been …

Homing-based gene drives are recently proposed interventions promising the area-wide,
species-specific genetic control of harmful insect populations. Here we characterise a first …

Lipophorin is an essential, highly expressed lipid transport protein that is secreted and
circulates in insect hemolymph. We hijacked the Anopheles coluzzii Lipophorin gene to …

The human malaria vector Anopheles gambiae is becoming increasingly resistant to
insecticides, spurring the development of genetic control strategies. CRISPR-Cas9 gene …

Indoor insecticide applications are the primary tool for reducing malaria transmission in the
Solomon Archipelago, a region where Anopheles farauti is the only common malaria vector …

Sustainable reductions in African malaria transmission require innovative tools for mosquito
control. One proposal involves the use of low-threshold gene drive in Anopheles vector …

Simple Summary Many insects are categorized as agricultural pests due to their ability to
transmit diseases and damage crops, which results in significant economic losses. Scientists …

Genetic control strategies are promising solutions for control of pest populations and
invasive species. Methods utilizing repeated releases of males such as Sterile Insect …