Matrices, scaffolds & carriers for cell delivery in nerve regeneration

ZZ Wang, SE Sakiyama-Elbert - Experimental neurology, 2019 - Elsevier
Nerve injuries can be life-long debilitating traumas that severely impact patients' quality of
life. While many acellular neural scaffolds have been developed to aid the process of nerve …

Using biomaterials to promote pro-regenerative glial phenotypes after nervous system injuries

R Thompson, S Sakiyama-Elbert - Biomedical Materials, 2018 - iopscience.iop.org
Trauma to either the central or peripheral nervous system (PNS) often leads to significant
loss of function and disability in patients. This high rate of long-term disability is due to the …

Schwann cell durotaxis can be guided by physiologically relevant stiffness gradients

EB Evans, SW Brady, A Tripathi… - Biomaterials …, 2018 - spj.science.org
Background Successful nerve regeneration depends upon directed migration of
morphologically specialized repair state Schwann cells across a nerve defect. Although …

Transcriptional heterogeneity between primary adult grey and white matter astrocytes underlie differences in modulation of in vitro myelination

IL Werkman, ML Dubbelaar, P van der Vlies… - Journal of …, 2020 - Springer
Background Multiple sclerosis (MS) is an inflammation-mediated demyelinating disease of
the central nervous system that eventually results in secondary axonal degeneration due to …

[HTML][HTML] Exploring the multiphysics of the brain during development, aging, and in neurological diseases

J Weickenmeier - Brain multiphysics, 2023 - Elsevier
The human brain remains an endless source of wonder and represents an intruiging
scientific frontier. Multiphysics approaches naturally lend themselves to combine our …

[PDF][PDF] Matrix Biology Plus

A Montgomery, J Westphal, AE Bryan, GM Harris - researchgate.net
Schwann cells (SCs) hold key roles in axonal function and maintenance in the peripheral
nervous system (PNS) and are a critical component to the regeneration process following …