Extracellular matrix‐mimetic hydrogels for treating neural tissue injury: a focus on fibrin, hyaluronic acid, and elastin‐like polypeptide hydrogels

DW Nelson, RJ Gilbert - Advanced healthcare materials, 2021 - Wiley Online Library
Neurological and functional recovery is limited following central nervous system injury and
severe injury to the peripheral nervous system. Extracellular matrix (ECM)‐mimetic …

Biomaterials for stem cell differentiation

E Dawson, G Mapili, K Erickson, S Taqvi… - Advanced drug delivery …, 2008 - Elsevier
The promise of cellular therapy lies in the repair of damaged organs and tissues in vivo as
well as generating tissue constructs in vitro for subsequent transplantation. Unfortunately …

[HTML][HTML] Long-distance growth and connectivity of neural stem cells after severe spinal cord injury

P Lu, Y Wang, L Graham, K McHale, M Gao, D Wu… - Cell, 2012 - cell.com
Neural stem cells (NSCs) expressing GFP were embedded into fibrin matrices containing
growth factor cocktails and grafted to sites of severe spinal cord injury. Grafted cells …

Electrospun nanofibers for neural tissue engineering

J **e, MR MacEwan, AG Schwartz, Y **a - Nanoscale, 2010 - pubs.rsc.org
Biodegradable nanofibers produced by electrospinning represent a new class of promising
scaffolds to support nerve regeneration. We begin with a brief discussion on the …

[HTML][HTML] Biomaterials for stem cell engineering and biomanufacturing

Y Xu, C Chen, PB Hellwarth, X Bao - Bioactive materials, 2019 - Elsevier
Recent years have witnessed the expansion of tissue failures and diseases. The uprising of
regenerative medicine converges the sight onto stem cell-biomaterial based therapy. Tissue …

The differentiation of embryonic stem cells seeded on electrospun nanofibers into neural lineages

J **e, SM Willerth, X Li, MR Macewan, A Rader… - Biomaterials, 2009 - Elsevier
Due to advances in stem cell biology, embryonic stem (ES) cells can be induced to
differentiate into a particular mature cell lineage when cultured as embryoid bodies …

Combining stem cells and biomaterial scaffolds for constructing tissues and cell delivery

SM Willerth, SE Sakiyama-Elbert - Stem Journal, 2019 - journals.sagepub.com
Combining stem cells with biomaterial scaffolds serves as a promising strategy for
engineering tissues for both in vitro and in vivo applications. This updated review details …

Engineering the embryoid body microenvironment to direct embryonic stem cell differentiation

AM Bratt‐Leal, RL Carpenedo… - Biotechnology …, 2009 - Wiley Online Library
Embryonic stem cells (ESCs) are pluripotent cells capable of differentiating into all somatic
and germ cell types. The intrinsic ability of pluripotent cells to generate a vast array of …

Challenges of stem cell therapy for spinal cord injury: human embryonic stem cells, endogenous neural stem cells, or induced pluripotent stem cells?

M Ronaghi, S Erceg, V Moreno-Manzano… - Stem …, 2010 - academic.oup.com
Spinal cord injury (SCI) causes myelopathy, damage to white matter, and myelinated fiber
tracts that carry sensation and motor signals to and from the brain. The gray matter damage …

[HTML][HTML] Hydrogel-assisted neuroregeneration approaches towards brain injury therapy: A state-of-the-art review

VA Kornev, EA Grebenik, AB Solovieva… - Computational and …, 2018 - Elsevier
Recent years have witnessed the development of an enormous variety of hydrogel-based
systems for neuroregeneration. Formed from hydrophilic polymers and comprised of up to …