The role of the retromer complex in aging-related neurodegeneration: a molecular and genomic review

C Reitz - Molecular Genetics and Genomics, 2015 - Springer
The retromer coat complex is a vital component of the intracellular trafficking mechanism
sorting cargo from the endosomes to the trans-Golgi network or to the cell surface. In recent …

Association between APOC1 Polymorphism and Alzheimer's Disease: A Case-Control Study and Meta-Analysis

Q Zhou, F Zhao, Z Lv, C Zheng, W Zheng, L Sun… - PloS one, 2014 - journals.plos.org
Background Previous association studies examining the relationship between the APOC1
polymorphism and susceptibility to Alzheimer's disease (AD) have shown conflicting results …

Genetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case-control cohort

LS Elias-Sonnenschein, S Helisalmi, T Natunen… - PloS one, 2013 - journals.plos.org
Objectives To understand the relation between risk genes for Alzheimer's disease (AD) and
their influence on biomarkers for AD, we examined the association of AD in the Finnish …

Meta-analysis of the Association between Alzheimer Disease and Variants in GAB2, PICALM, and SORL1

Z Wang, H Lei, M Zheng, Y Li, Y Cui, F Hao - Molecular neurobiology, 2016 - Springer
The genetic variants play a crucial role in the pathogenesis of Alzheimer's disease (AD),
while the relationships of specific single nucleotide polymorphisms (SNPs) with AD are still …

Integrating prospective longitudinal data: modeling personality and health in the Terman Life Cycle and Hawaii Longitudinal Studies.

ML Kern, SE Hampson, LR Goldberg… - Developmental …, 2014 - psycnet.apa.org
The present study used a collaborative framework to integrate 2 long-term prospective
studies: the Terman Life Cycle Study and the Hawaii Personality and Health Longitudinal …

Association between Sirtuin 2 gene rs10410544 polymorphism and depression in Alzheimer's disease in two independent European samples

S Porcelli, R Salfi, A Politis, AR Atti, D Albani… - Journal of Neural …, 2013 - Springer
Among the several genes associated with late-onset Alzheimer's disease (LOAD), recently,
Sirtuin genes have roused a growing interest because of their involvement in metabolic …

Role of neurodevelopment involved genes in psychiatric comorbidities and modulation of inflammatory processes in Alzheimer's disease

P Stefano, C Concetta, D Luigi, C Marco… - Journal of the …, 2016 - Elsevier
Introduction With the increase of the population's average age, Alzheimer's disease (AD) is
becoming one of the most disabling diseases worldwide. Recently, neurodevelopment …

[HTML][HTML] Interaction between PPAR γ and SORL1 gene with Late-Onset Alzheimer's disease in Chinese Han Population

H Zhang, W Zheng, L Hua, Y Wang, J Li, H Bai… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Aims To investigate the impact of sortilin-related receptor 1 gene 1 (SORL1) and peroxisome
proliferator activated receptor gamma (PPAR G) gene single nucleotide polymorphisms …

Association between SORL1 polymorphisms and the risk of Alzheimer's disease

L Cong, X Kong, J Wang, J Du, Z Xu… - Journal of Integrative …, 2018 - content.iospress.com
A meta-analysis was performed to identify empirical data assessing the effects of a single
nucleotide polymorphisms of sortilin-related receptor on Alzheimer's disease based on 14 …

SorLA deficiency dissects amyloid pathology from tau and cholinergic neurodegeneration in a mouse model of Alzheimer's disease

S Capsoni, AS Carlo, D Vignone… - Journal of …, 2013 - content.iospress.com
Sortilin-related receptor with A-type repeats (SorLA, also known as LR11) has been
implicated in Alzheimer's disease (AD). Thus, genetic studies associated SorLA gene …