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The evolution of nucleoside analogue antivirals: A review for chemists and non-chemists. Part 1: Early structural modifications to the nucleoside scaffold
This is the first of two invited articles reviewing the development of nucleoside-analogue
antiviral drugs, written for a target audience of virologists and other non-chemists, as well as …
antiviral drugs, written for a target audience of virologists and other non-chemists, as well as …
Approved antiviral drugs over the past 50 years
Since the first antiviral drug, idoxuridine, was approved in 1963, 90 antiviral drugs
categorized into 13 functional groups have been formally approved for the treatment of the …
categorized into 13 functional groups have been formally approved for the treatment of the …
Trends and strategies to combat viral infections: A review on FDA approved antiviral drugs
The infectious microscopic viruses invade living cells to reproduce themselves, and causes
chronic infections such as HIV/AIDS, hepatitis B and C, flu, etc. in humans which may lead to …
chronic infections such as HIV/AIDS, hepatitis B and C, flu, etc. in humans which may lead to …
Getting to HBV cure: The promising paths forward
Chronic HBV infection is a global public health burden estimated to impact nearly 300
million persons worldwide. Despite the advent of potent antiviral agents that effectively …
million persons worldwide. Despite the advent of potent antiviral agents that effectively …
Tenofovir alafenamide versus tenofovir disoproxil fumarate for the treatment of patients with HBeAg-negative chronic hepatitis B virus infection: a randomised, double …
Background The novel prodrug tenofovir alafenamide delivers the nucleotide reverse
transcriptase inhibitor tenofovir to target cells more efficiently at a lower dose than tenofovir …
transcriptase inhibitor tenofovir to target cells more efficiently at a lower dose than tenofovir …
KASL clinical practice guidelines for management of chronic hepatitis B
Korean Association for the Study of the … - Clinical and …, 2019 - pmc.ncbi.nlm.nih.gov
Diseases (AASLD) also presented and continued to revise their clinical practice guidelines,
and the latest updates were in 2015, 2017, and 2018. However, since the medical …
and the latest updates were in 2015, 2017, and 2018. However, since the medical …
[HTML][HTML] EASL clinical practice guidelines: management of chronic hepatitis B virus infection
European Association For The Study Of The Liver - Journal of hepatology, 2012 - Elsevier
Our understanding of the natural history of hepatitis B virus (HBV) infection and the potential
for therapy of the resultant disease is continuously improving. New data have become …
for therapy of the resultant disease is continuously improving. New data have become …
Hepatitis B virus infection
YF Liaw, CM Chu - The lancet, 2009 - thelancet.com
Since the introduction of the hepatitis B vaccine and other preventive measures, the
worldwide prevalence of hepatitis B infection has fallen. However, chronic infection remains …
worldwide prevalence of hepatitis B infection has fallen. However, chronic infection remains …
Chronic hepatitis B: virology, natural history, current management and a glimpse at future opportunities
The host immune system plays an important role in chronic hepatitis B (CHB), both in viral
clearance and hepatocellular damage. Advances in our understanding of the natural history …
clearance and hepatocellular damage. Advances in our understanding of the natural history …
Guideline of prevention and treatment for chronic hepatitis B (2015 update)
J Hou, G Wang, F Wang, J Cheng… - Journal of clinical …, 2017 - pmc.ncbi.nlm.nih.gov
The Chinese Society of Hepatology, Chinese Medical Association (CMA) and the Society of
Infectious Diseases, CMA organized relevant native experts to establish this Guideline of …
Infectious Diseases, CMA organized relevant native experts to establish this Guideline of …