Current developments of coumarin compounds in medicinal chemistry

XM Peng, G LV Damu, C He Zhou - Current pharmaceutical …, 2013 - benthamdirect.com
Coumarin compounds represent an important type of naturally occurring and synthetic
oxygen-containing heterocycles with typical benzopyrone framework. This type of special …

Coumarin compounds in medicinal chemistry: some important examples from the last years

TM Pereira, DP Franco, F Vitorio… - Current topics in …, 2018 - benthamdirect.com
Coumarins are natural products characterized as 1, 2 benzopyrones widely distributed in
plants, as well as, in many species of fungi and bacteria. Nowadays, many synthetic …

Design and synthesis of oxazepine derivatives from sulfonamide Schiff bases as antimicrobial and antioxidant agents with low cytotoxicity and hemolytic prospective

SA Hassan, DM Aziz, MN Abdullah, AR Bhat… - Journal of Molecular …, 2023 - Elsevier
The eco-friendly sonication and microwave irradiation techniques were used for the straight
forward synthesis of the Schiff base platform from sulfathiazole. Herein, Schiff bases were …

Eco-friendly synthesis, characterization, in-silico ADMET and molecular docking analysis of novel carbazole derivatives as antibacterial and antifungal agents

O Merzouki, N Arrousse, A El Barnossi… - Journal of Molecular …, 2023 - Elsevier
In search of novel biologically potent compounds, three novel organic molecules have been
synthesized. The structures of the prepared compounds have been characterized by …

Synthesis, antioxidant and anticholinesterase activities of novel coumarylthiazole derivatives

BZ Kurt, I Gazioglu, F Sonmez, M Kucukislamoglu - Bioorganic chemistry, 2015 - Elsevier
A newly series of coumarylthiazole derivatives containing aryl urea/thiourea groups were
synthesized and their inhibitory effects on acetylcholinesterase (AChE) and …

Synthesis, Characterization and In Vitro Anticancer Activity of C‐5 Curcumin Analogues with Potential to Inhibit TNF‐α‐Induced NF‐κB Activation

A Anthwal, BK Thakur, MSM Rawat… - BioMed research …, 2014 - Wiley Online Library
In a search of new compounds active against cancer, synthesis of a series of C‐5 curcumin
analogues was carried out. The new compounds demonstrated good cytotoxicity against …

Design, synthesis and docking study of novel coumarin ligands as potential selective acetylcholinesterase inhibitors

F Sonmez, B Zengin Kurt, I Gazioglu… - Journal of enzyme …, 2017 - Taylor & Francis
New coumaryl-thiazole derivatives with the acetamide moiety as a linker between the alkyl
chains and/or the heterocycle nucleus were synthesized and in vitro tested as …

New tailored substituted benzothiazole Schiff base Cu (II)/Zn (II) antitumor drug entities: effect of substituents on DNA binding profile, antimicrobial and cytotoxic …

S Zehra, M Shavez Khan, I Ahmad… - Journal of Biomolecular …, 2019 - Taylor & Francis
New tailored Cu (II) & Zn (II) metal-based antitumor drug entities were synthesized from
substituted benzothiazole o‒vanillin Schiff base ligands. The complexes were thoroughly …

Antifungal activity, SAR and physicochemical correlation of some thiazole-1, 3, 5-triazine derivatives

UP Singh, HR Bhat, P Gahtori - Journal de mycologie médicale, 2012 - Elsevier
OBJECTIVE: Present research communication was towards the investigation of antifungal
minimum inhibitory concentration (MIC) and minimum fingicidal concentration (MFC) activity …

Coumarin-derived azolyl ethanols: Synthesis, antimicrobial evaluation and preliminary action mechanism

XM Peng, KV Kumar, GLV Damu, CH Zhou - Science China Chemistry, 2016 - Springer
A series of coumarin-derived azolyl ethanols including imidazolyl, triazolyl, tetrazolyl,
benzotriazolyl, thiol-imidazolyl and thiol-triazolyl ones were conveniently synthesized and …