Non–small cell lung cancer

DS Ettinger, W Akerley, G Bepler, MG Blum… - Journal of the national …, 2010 - jnccn.org
Overview Lung cancer is the leading cause of cancer-related death in the United States. An
estimated 219,440 new cases (116,090 men; 103,350 women) of lung and bronchus cancer …

Report of the AAPM Task Group No. 105: Issues associated with clinical implementation of Monte Carlo‐based photon and electron external beam treatment planning

IJ Chetty, B Curran, JE Cygler, JJ DeMarco… - Medical …, 2007 - Wiley Online Library
The Monte Carlo (MC) method has been shown through many research studies to calculate
accurate dose distributions for clinical radiotherapy, particularly in heterogeneous patient …

Ferroptosis inhibitor alleviates Radiation-induced lung fibrosis (RILF) via down-regulation of TGF-β1

X Li, L Duan, S Yuan, X Zhuang, T Qiao, J He - Journal of inflammation, 2019 - Springer
Background Radiation-induced lung fibrosis (RILF) is a severe and life-threatening
complication of thoracic radiotherapy. Cell death is the key issue in RILF. Ferroptosis is a …

[HTML][HTML] Heart dose is an independent dosimetric predictor of overall survival in locally advanced non–small cell lung cancer

CK Speirs, TA DeWees, S Rehman… - Journal of Thoracic …, 2017 - Elsevier
Introduction In the randomized trial of standard-versus high-dose chemoradiotherapy for
locally advanced (LA) NSCLC (Radiation Therapy Oncology Group 0617), overall survival …

Stereotactic body radiotherapy (SBRT) for operable stage I non–small-cell lung cancer: can SBRT be comparable to surgery?

H Onishi, H Shirato, Y Nagata, M Hiraoka… - International Journal of …, 2011 - Elsevier
PURPOSE: To review treatment outcomes for stereotactic body radiotherapy (SBRT) in
medically operable patients with Stage I non–small-cell lung cancer (NSCLC), using a …

[HTML][HTML] Higher radiation dose to the immune cells correlates with worse tumor control and overall survival in patients with stage III NSCLC: a secondary analysis of …

JY **, C Hu, Y **ao, H Zhang, R Paulus, SG Ellsworth… - Cancers, 2021 - mdpi.com
Simple Summary Emerging evidence indicates that the immune system plays an important
role in controlling tumors during radiotherapy, and radiation-induced immune toxicity such …

Effect of midtreatment PET/CT-adapted radiation therapy with concurrent chemotherapy in patients with locally advanced non–small-cell lung cancer: A phase 2 …

FM Kong, RK Ten Haken, M Schipper, KA Frey… - JAMA …, 2017 - jamanetwork.com
Importance Our previous studies demonstrated that tumors significantly decrease in size and
metabolic activity after delivery of 45 Gy of fractionated radiatiotherapy (RT), and that …

Universal survival curve and single fraction equivalent dose: useful tools in understanding potency of ablative radiotherapy

C Park, L Papiez, S Zhang, M Story… - International Journal of …, 2008 - Elsevier
PURPOSE: Overprediction of the potency and toxicity of high-dose ablative radiotherapy
such as stereotactic body radiotherapy (SBRT) by the linear quadratic (LQ) model led to …

Intensity-modulated proton therapy reduces the dose to normal tissue compared with intensity-modulated radiation therapy or passive scattering proton therapy and …

X Zhang, Y Li, X Pan, L **aoqiang, R Mohan… - International Journal of …, 2010 - Elsevier
PURPOSE: To compare dose volume histograms of intensity-modulated proton therapy
(IMPT) with those of intensity-modulated radiation therapy (IMRT) and passive scattering …

Systemic review of the patterns of failure following stereotactic body radiation therapy in early-stage non-small-cell lung cancer: clinical implications

A Chi, Z Liao, NP Nguyen, J Xu, B Stea… - Radiotherapy and …, 2010 - Elsevier
PURPOSE: To analyze the patterns of failure, the toxicity profile, and the factors influencing
efficacy of stereotactic body radiation (SBRT) for early-stage non-small-cell lung cancer …