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[HTML][HTML] Glucagon-like peptide-1: A multi-faceted anti-inflammatory agent
Inflammation contributes to many chronic conditions. It is often associated with circulating
pro-inflammatory cytokines and immune cells. GLP-1 levels correlate with disease severity …
pro-inflammatory cytokines and immune cells. GLP-1 levels correlate with disease severity …
Steatotic liver disease: pathophysiology and emerging pharmacotherapies
Steatotic liver disease (SLD) displays a dynamic and complex disease phenotype.
Consequently, the metabolic dysfunction-associated steatotic liver disease …
Consequently, the metabolic dysfunction-associated steatotic liver disease …
Glucagon‐like peptide agonists: a prospective review
Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) have emerged as
promising therapeutic options for addressing Type‐2 diabetes, obesity, and related …
promising therapeutic options for addressing Type‐2 diabetes, obesity, and related …
Effects of once‐weekly semaglutide on appetite, energy intake, control of eating, food preference and body weight in subjects with obesity
Aim The aim of this trial was to investigate the mechanism of action for body weight loss with
semaglutide. Materials and methods This randomised, double‐blind, placebo‐controlled …
semaglutide. Materials and methods This randomised, double‐blind, placebo‐controlled …
The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss
A Secher, J Jelsing, AF Baquero… - The Journal of clinical …, 2014 - jci.org
Liraglutide is a glucagon-like peptide-1 (GLP-1) analog marketed for the treatment of type 2
diabetes. Besides lowering blood glucose, liraglutide also reduces body weight. It is not fully …
diabetes. Besides lowering blood glucose, liraglutide also reduces body weight. It is not fully …
Obesity and diabetes: an update
S Verma, ME Hussain - Diabetes & Metabolic Syndrome: Clinical Research …, 2017 - Elsevier
The twin epidemic of obesity and diabetes is a major crisis globally. Several epidemiologic
studies reveal the parallel escalation of obesity and diabetes. The term 'diabesity'expresses …
studies reveal the parallel escalation of obesity and diabetes. The term 'diabesity'expresses …
Weight loss variability with SGLT2 inhibitors and GLP‐1 receptor agonists in type 2 diabetes mellitus and obesity: mechanistic possibilities
We are facing a global epidemic of obesity and type 2 diabetes. Weight loss, in the context of
obesity and type 2 diabetes, may improve glycaemic control and weight‐related …
obesity and type 2 diabetes, may improve glycaemic control and weight‐related …
Physiology of proglucagon peptides: role of glucagon and GLP-1 in health and disease
DA Sandoval, DA D'Alessio - Physiological reviews, 2015 - journals.physiology.org
The preproglucagon gene (Gcg) is expressed by specific enteroendocrine cells (L-cells) of
the intestinal mucosa, pancreatic islet α-cells, and a discrete set of neurons within the …
the intestinal mucosa, pancreatic islet α-cells, and a discrete set of neurons within the …
Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells
Exercise, obesity and type 2 diabetes are associated with elevated plasma concentrations of
interleukin-6 (IL-6). Glucagon-like peptide-1 (GLP-1) is a hormone that induces insulin …
interleukin-6 (IL-6). Glucagon-like peptide-1 (GLP-1) is a hormone that induces insulin …
Glucagon-like peptide-1 receptor agonists and dual glucose-dependent insulinotropic polypeptide/glucagon-like peptide-1 receptor agonists in the treatment of …
EM Muzurović, Š Volčanšek… - Journal of …, 2022 - journals.sagepub.com
The obesity pandemic is accompanied by increased risk of develo** metabolic syndrome
(MetS) and related conditions: non-alcoholic fatty liver disease (NAFLD)/non-alcoholic …
(MetS) and related conditions: non-alcoholic fatty liver disease (NAFLD)/non-alcoholic …