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Regulation of signaling from the epidermal growth factor family
AW Burgess - The Journal of Physical Chemistry B, 2022 - ACS Publications
The epidermal growth factor (EGF) system has allowed chemists, biologists, and clinicians to
improve our understanding of cell production and cancer therapy. The discovery of EGF led …
improve our understanding of cell production and cancer therapy. The discovery of EGF led …
Engineered synthetic nanobody-based biosensors for electrochemical detection of epidermal growth factor receptor
Two engineered synthetic nanobody-based nanobiocomposite platforms were developed
for label-free electrochemical detection of the epithelial growth factor receptor (EGFR) …
for label-free electrochemical detection of the epithelial growth factor receptor (EGFR) …
Identification of meflin as a potential marker for mesenchymal stromal cells
K Maeda, A Enomoto, A Hara, N Asai, T Kobayashi… - Scientific reports, 2016 - nature.com
Bone marrow-derived mesenchymal stromal cells (BM-MSCs) in culture are derived from BM
stromal cells or skeletal stem cells. Whereas MSCs have been exploited in clinical medicine …
stromal cells or skeletal stem cells. Whereas MSCs have been exploited in clinical medicine …
LRIG proteins in glioma: functional roles, molecular mechanisms, and potential clinical implications
F Mao, B Wang, Q **ao, F Cheng, T Lei… - Journal of the Neurological …, 2017 - Elsevier
Gliomas are the most common intracranial tumors of the nervous system. These tumors are
characterized by unlimited cell proliferation and excessive invasiveness. Despite the …
characterized by unlimited cell proliferation and excessive invasiveness. Despite the …
LRIG1 is a conserved EGFR regulator involved in melanoma development, survival and treatment resistance
O Billing, Y Holmgren, D Nosek, H Hedman… - Oncogene, 2021 - nature.com
Leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) is a pan-negative
regulator of receptor tyrosine kinase (RTK) signaling and a tumor suppressor in several …
regulator of receptor tyrosine kinase (RTK) signaling and a tumor suppressor in several …
Essential role of linx/Islr2 in the development of the forebrain anterior commissure
Linx is a member of the leucine-rich repeat and immunoglobulin family of membrane
proteins which has critical roles in the development of the peripheral nervous system and …
proteins which has critical roles in the development of the peripheral nervous system and …
Harnessing LRIG1-mediated inhibition of receptor tyrosine kinases for cancer therapy
Leucine-rich repeats and immunoglobulin-like domains containing protein 1 (LRIG1) is an
endogenous feedback regulator of receptor tyrosine kinases (RTKs) and was recently …
endogenous feedback regulator of receptor tyrosine kinases (RTKs) and was recently …
Hypothesis: Do LRIG proteins regulate stem cell quiescence by promoting BMP signaling?
C Herdenberg, H Hedman - Stem Cell Reviews and Reports, 2023 - Springer
Leucine-rich repeats and immunoglobulin-like domains (LRIG) proteins are evolutionarily
conserved integral membrane proteins. Mammalian LRIG1 regulates stem cell quiescence …
conserved integral membrane proteins. Mammalian LRIG1 regulates stem cell quiescence …
LRIGs: A prognostically significant family with emerging therapeutic competence against cancers
U Malik, A Javed - Current Cancer Drug Targets, 2017 - ingentaconnect.com
The human leucine-rich repeats and immunoglobulin like domains (LRIG) are evolutionary
conserved family of single-pass transmembrane proteins. LRIG gene family includes three …
conserved family of single-pass transmembrane proteins. LRIG gene family includes three …
Analysis of toll‐like receptors in human milk: Detection of membrane‐bound and soluble forms
C Cattaneo, A Caramaschi, E Uga… - Journal of …, 2019 - Wiley Online Library
The bioactive and anti‐inflammatory role of human milk components has been recognized;
active milk components include soluble forms of Toll‐like receptors (TLRs). Preterm babies …
active milk components include soluble forms of Toll‐like receptors (TLRs). Preterm babies …