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Visible-to-NIR-light activated release: from small molecules to nanomaterials
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …
Next-generation interfaces for studying neural function
Monitoring and modulating the diversity of signals used by neurons and glia in a closed-loop
fashion is necessary to establish causative links between biochemical processes within the …
fashion is necessary to establish causative links between biochemical processes within the …
Structural Elucidation of a metagenomic urethanase and its engineering towards enhanced hydrolysis profiles
T Bayer, GJ Palm, L Berndt, H Meinert… - Angewandte Chemie …, 2024 - Wiley Online Library
While plastics like polyethylene terephthalate can already be degraded efficiently by the
activity of hydrolases, other synthetic polymers like polyurethanes (PUs) and polyamides …
activity of hydrolases, other synthetic polymers like polyurethanes (PUs) and polyamides …
Water-soluble BODIPY photocages with tunable cellular localization
D Kand, P Liu, MX Navarro, LJ Fischer… - Journal of the …, 2020 - ACS Publications
Photoactivation of bioactive molecules allows manipulation of cellular processes with high
spatiotemporal precision. The recent emergence of visible-light excitable photoprotecting …
spatiotemporal precision. The recent emergence of visible-light excitable photoprotecting …
Clip chemistry: diverse (bio)(macro) molecular and material function through breaking covalent bonds
In the two decades since the introduction of the “click chemistry” concept, the toolbox of “click
reactions” has continually expanded, enabling chemists, materials scientists, and biologists …
reactions” has continually expanded, enabling chemists, materials scientists, and biologists …
Lysosome-targeted multifunctional lipid probes reveal the sterol transporter NPC1 as a sphingosine interactor
J Altuzar, J Notbohm, F Stein, P Haberkant… - Proceedings of the …, 2023 - pnas.org
Lysosomes are catabolic organelles involved in macromolecular digestion, and their
dysfunction is associated with pathologies ranging from lysosomal storage disorders to …
dysfunction is associated with pathologies ranging from lysosomal storage disorders to …
Fluorogenic chemical probes for wash-free imaging of cell membrane damage in ferroptosis, necrosis, and axon Injury
P Mauker, D Beckmann, A Kitowski… - Journal of the …, 2024 - ACS Publications
Selectively labeling cells with damaged membranes is needed not only for identifying dead
cells in culture, but also for imaging membrane barrier dysfunction in pathologies in vivo …
cells in culture, but also for imaging membrane barrier dysfunction in pathologies in vivo …
Light-triggered release of photocaged therapeutics-Where are we now?
The current available therapeutics face several challenges such as the development of ideal
drug delivery systems towards the goal of personalized treatments for patients benefit. The …
drug delivery systems towards the goal of personalized treatments for patients benefit. The …
Trifunctional lipid probes for comprehensive studies of single lipid species in living cells
D Höglinger, A Nadler, P Haberkant… - Proceedings of the …, 2017 - pnas.org
Lipid-mediated signaling events regulate many cellular processes. Investigations of the
complex underlying mechanisms are difficult because several different methods need to be …
complex underlying mechanisms are difficult because several different methods need to be …
Organelle‐targeted BODIPY photocages: visible‐light‐mediated subcellular photorelease
Photocaging facilitates non‐invasive and precise spatio‐temporal control over the release of
biologically relevant small‐and macro‐molecules using light. However, sub‐cellular …
biologically relevant small‐and macro‐molecules using light. However, sub‐cellular …