[HTML][HTML] Delineating the activation mechanism and conformational landscape of a class BG protein-coupled receptor glucagon receptor

Y Wang, M Li, W Liang, X Shi, J Fan, R Kong… - Computational and …, 2022 - Elsevier
Class BG protein-coupled receptors (GPCRs) are important targets in the treatment of
metabolic syndrome and diabetes. Although multiple structures of class B GPCRs–G protein …

[KNJIGA][B] Genome-scale algorithm design: bioinformatics in the era of high-throughput sequencing

V Mäkinen, D Belazzougui, F Cunial, AI Tomescu - 2023 - books.google.com
Presenting the fundamental algorithms and data structures that power bioinformatics
workflows, this book covers a range of topics from the foundations of sequence analysis …

Algorithms and complexity on indexing founder graphs

M Equi, T Norri, J Alanko, B Cazaux, AI Tomescu… - Algorithmica, 2023 - Springer
We study the problem of matching a string in a labeled graph. Previous research has shown
that unless the Orthogonal Vectors Hypothesis (OVH) is false, one cannot solve this problem …

Applying and optimizing NLP model with CARU

KH Chan, SK Im, G Pau - 2022 8th International Conference on …, 2022 - ieeexplore.ieee.org
RNN for language models can solve the problem of sparse content and high-dimensional
features in traditional N-gram models. However, due to the problems of overfitting and …

Fast parallel construction of variable-length Markov chains

J Gustafsson, P Norberg, JR Qvick-Wester, A Schliep - BMC bioinformatics, 2021 - Springer
Background Alignment-free methods are a popular approach for comparing biological
sequences, including complete genomes. The methods range from probability distributions …

Application of Markov Model‐Based IoT in Agricultural Insurance and Risk Management

W Chen, Y Jiang - Mobile information systems, 2021 - Wiley Online Library
As the foundation of the national economy, agriculture is a high‐risk, weak industry. Affected
by many factors, agricultural production is subject to catastrophe risks from time to time …

Fast and compact matching statistics analytics

F Cunial, O Denas, D Belazzougui - Bioinformatics, 2022 - academic.oup.com
Motivation Fast, lightweight methods for comparing the sequence of ever larger assembled
genomes from ever growing databases are increasingly needed in the era of accurate long …

Smaller fully-functional bidirectional BWT indexes

D Belazzougui, F Cunial - … on String Processing and Information Retrieval, 2020 - Springer
Burrows-Wheeler indexes that support both extending and contracting any substring of the
text T of length n on which they are built, in any direction, provide substantial flexibility in …

[PDF][PDF] BWT tunneling

U Baier - 2021 - oparu.uni-ulm.de
The Burrows-Wheeler-Transform (BWT) is a well-known reversible text transformation
invented by David J. Wheeler around 1978 and published by Mike Burrows and David J …

[KNJIGA][B] Genomic signatures in viruses

J Gustafsson - 2023 - gupea.ub.gu.se
In an age of global pandemics, studying how viruses and their genomes evolve is of great
importance. It has previously been found that the genomes of many eukaryotes and …