Clinical relevance of biomarkers of oxidative stress

J Frijhoff, PG Winyard, N Zarkovic… - Antioxidants & redox …, 2015 - liebertpub.com
Significance: Oxidative stress is considered to be an important component of various
diseases. A vast number of methods have been developed and used in virtually all diseases …

[HTML][HTML] Oxidative stress

GJ Burton, E Jauniaux - Best practice & research Clinical obstetrics & …, 2011 - Elsevier
Considerable evidence implicates oxidative stress in the pathophysiology of many
complications of human pregnancy, and this topic has now become a major focus of both …

Oxidative stress and antioxidants in hypertension–a current review

N Sinha, P Kumar Dabla - Current hypertension reviews, 2015 - ingentaconnect.com
Free radicals or reactive oxygen species (ROS) are generated by oxygen metabolism which
is balanced by the rate of oxidant formation and the rate of oxidant elimination. Oxidative …

Cross talk between mitochondria and NADPH oxidases

S Dikalov - Free Radical Biology and Medicine, 2011 - Elsevier
Reactive oxygen species (ROS) play an important role in physiological and pathological
processes. In recent years, a feed-forward regulation of the ROS sources has been reported …

[HTML][HTML] Oxidative stress and hypertension: Possibility of hypertension therapy with antioxidants

A Baradaran, H Nasri… - Journal of research in …, 2014 - ncbi.nlm.nih.gov
Hypertension is a major risk factor for myocardial infarction, heart failure, stroke, peripheral
arterial disease, and aortic aneurysm, and is a cause of chronic kidney disease …

The role of oxidative stress in the pathophysiology of hypertension

R Rodrigo, J González, F Paoletto - Hypertension Research, 2011 - nature.com
Hypertension is considered to be the most important risk factor in the development of
cardiovascular disease. An increasing body of evidence suggests that oxidative stress …

Functional role of mitochondrial reactive oxygen species in physiology

PR Angelova, AY Abramov - Free radical biology and medicine, 2016 - Elsevier
The major energy generator in the cell–mitochondria produce reactive oxygen species as a
by-product of a number of enzymatic reactions and the production of ATP. Emerging …

Reactive oxygen species and vascular biology: implications in human hypertension

RM Touyz, AM Briones - Hypertension research, 2011 - nature.com
Increased vascular production of reactive oxygen species (ROS; termed oxidative stress)
has been implicated in various chronic diseases, including hypertension. Oxidative stress is …

NADPH oxidases, reactive oxygen species, and hypertension: clinical implications and therapeutic possibilities

TM Paravicini, RM Touyz - Diabetes care, 2008 - Am Diabetes Assoc
Reactive oxygen species (ROS) influence many physiological processes including host
defense, hormone biosynthesis, fertilization, and cellular signaling. Increased ROS …

Mitochondrial Ca2+ and regulation of the permeability transition pore

S Hurst, J Hoek, SS Sheu - Journal of bioenergetics and biomembranes, 2017 - Springer
The mitochondrial permeability transition pore was originally described in the 1970's as a
Ca 2+ activated pore and has since been attributed to the pathogenesis of many diseases …