Microfluidic formulation of topological hydrogels for microtissue engineering

KO Rojek, M Cwiklinska, J Kuczak… - Chemical …, 2022 - ACS Publications
Microfluidics has recently emerged as a powerful tool in generation of submillimeter-sized
cell aggregates capable of performing tissue-specific functions, so-called microtissues, for …

Microfluidic fabrication of microparticles for biomedical applications

W Li, L Zhang, X Ge, B Xu, W Zhang, L Qu… - Chemical Society …, 2018 - pubs.rsc.org
Droplet microfluidics offers exquisite control over the flows of multiple fluids in microscale,
enabling fabrication of advanced microparticles with precisely tunable structures and …

Cell culture in microfluidic droplets

S Sart, G Ronteix, S Jain, G Amselem… - Chemical …, 2022 - ACS Publications
Cell manipulation in droplets has emerged as one of the great successes of microfluidic
technologies, with the development of single-cell screening. However, the droplet format has …

[HTML][HTML] Core-shell microparticles: Generation approaches and applications

FM Galogahi, Y Zhu, H An, NT Nguyen - Journal of science: advanced …, 2020 - Elsevier
Micro-nanoscale core–shell particles are distinguishable from other particle types because
of their unique composition. Core-shell particles combine the features of both the core and …

Spheroids-on-a-chip: Recent advances and design considerations in microfluidic platforms for spheroid formation and culture

K Moshksayan, N Kashaninejad, ME Warkiani… - Sensors and Actuators B …, 2018 - Elsevier
A cell spheroid is a three-dimensional (3D) aggregation of cells. Synthetic, in-vitro spheroids
provide similar metabolism, proliferation, and species concentration gradients to those found …

Cellular capsules as a tool for multicellular spheroid production and for investigating the mechanics of tumor progression in vitro

K Alessandri, BR Sarangi… - Proceedings of the …, 2013 - National Acad Sciences
Deciphering the multifactorial determinants of tumor progression requires standardized high-
throughput preparation of 3D in vitro cellular assays. We present a simple microfluidic …

Drip** and jetting in microfluidic multiphase flows applied to particle and fibre synthesis

JK Nunes, SSH Tsai, J Wan… - Journal of physics D …, 2013 - iopscience.iop.org
Drip** and jetting regimes in microfluidic multiphase flows have been investigated
extensively, and this review summarizes the main observations and physical …

Emerging tumor-on-chips with electrochemical biosensors

L Lei, B Ma, C Xu, H Liu - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
Cancer, one of the most dangerous diseases with a high mortality rate, has attracted much
attention and interest. Advances in tissue engineering and microfluidics have led to the …

Cell spheroids as a versatile research platform: formation mechanisms, high throughput production, characterization and applications

MC Decarli, R Amaral, DP Dos Santos, LB Tofani… - …, 2021 - iopscience.iop.org
Abstract Three-dimensional (3D) cell culture has tremendous advantages to closely mimic
the in vivo architecture and microenvironment of healthy tissue and organs, as well as of …

Recent methods of droplet microfluidics and their applications in spheroids and organoids

Y Wang, M Liu, Y Zhang, H Liu, L Han - Lab on a Chip, 2023 - pubs.rsc.org
Droplet microfluidic techniques have long been known as a high-throughput approach for
cell manipulation. The capacity to compartmentalize cells into picolitre droplets in …