The matrix in cancer
TR Cox - Nature Reviews Cancer, 2021 - nature.com
The extracellular matrix is a fundamental, core component of all tissues and organs, and is
essential for the existence of multicellular organisms. From the earliest stages of organism …
essential for the existence of multicellular organisms. From the earliest stages of organism …
Insights into the post-translational modification and its emerging role in sha** the tumor microenvironment
More and more in-depth studies have revealed that the occurrence and development of
tumors depend on gene mutation and tumor heterogeneity. The most important …
tumors depend on gene mutation and tumor heterogeneity. The most important …
Spatially aware dimension reduction for spatial transcriptomics
Spatial transcriptomics are a collection of genomic technologies that have enabled
transcriptomic profiling on tissues with spatial localization information. Analyzing spatial …
transcriptomic profiling on tissues with spatial localization information. Analyzing spatial …
Characteristics of the cancer stem cell niche and therapeutic strategies
F Ju, MM Atyah, N Horstmann, S Gul, R Vago… - Stem Cell Research & …, 2022 - Springer
Distinct regions harboring cancer stem cells (CSCs) have been identified within the
microenvironment of various tumors, and as in the case of their healthy counterparts, these …
microenvironment of various tumors, and as in the case of their healthy counterparts, these …
Biophysics in tumor growth and progression: from single mechano-sensitive molecules to mechanomedicine
Evidence from physical sciences in oncology increasingly suggests that the interplay
between the biophysical tumor microenvironment and genetic regulation has significant …
between the biophysical tumor microenvironment and genetic regulation has significant …
Modified chitosan: insight on biomedical and industrial applications
Abstract Chitosan (CS), a by–product of chitin deacetylation can be useful in a broad range
of purposes, to mention agriculture, pharmaceuticals, material science, food and nutrition …
of purposes, to mention agriculture, pharmaceuticals, material science, food and nutrition …
Into the tissues: Extracellular matrix and its artificial substitutes: Cell signalling mechanisms
A Bandzerewicz, A Gadomska-Gajadhur - Cells, 2022 - mdpi.com
The existence of orderly structures, such as tissues and organs is made possible by cell
adhesion, ie, the process by which cells attach to neighbouring cells and a supporting …
adhesion, ie, the process by which cells attach to neighbouring cells and a supporting …
The extracellular matrix: its composition, function, remodeling, and role in tumorigenesis
The extracellular matrix (ECM) is a ubiquitous member of the body and is key to the
maintenance of tissue and organ integrity. Initially thought to be a bystander in many cellular …
maintenance of tissue and organ integrity. Initially thought to be a bystander in many cellular …
Focal adhesion dynamics in cellular function and disease
YG Mishra, B Manavathi - Cellular signalling, 2021 - Elsevier
Acting as a bridge between the cytoskeleton of the cell and the extra cellular matrix (ECM),
the cell-ECM adhesions with integrins at their core, play a major role in cell signalling to …
the cell-ECM adhesions with integrins at their core, play a major role in cell signalling to …
Identification and validation of an anoikis-associated gene signature to predict clinical character, stemness, IDH mutation, and immune filtration in glioblastoma
Z Sun, Y Zhao, Y Wei, X Ding, C Tan… - Frontiers in …, 2022 - frontiersin.org
Background Glioblastoma (GBM) is the most prominent and aggressive primary brain tumor
in adults. Anoikis is a specific form of programmed cell death that plays a key role in tumor …
in adults. Anoikis is a specific form of programmed cell death that plays a key role in tumor …