Harnessing the potential of hydrogels for advanced therapeutic applications: Current achievements and future directions

P Lu, D Ruan, M Huang, M Tian, K Zhu… - Signal transduction and …, 2024 - nature.com
The applications of hydrogels have expanded significantly due to their versatile, highly
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …

Customizing nano-chitosan for sustainable drug delivery

M Saeedi, O Vahidi, MR Moghbeli, S Ahmadi… - Journal of Controlled …, 2022 - Elsevier
Chitosan is a natural polymer with acceptable biocompatibility, biodegradability, and
mechanical stability; hence, it has been widely appraised for drug and gene delivery …

[HTML][HTML] Biopolymer-based composites for tissue engineering applications: A basis for future opportunities

P Zarrintaj, F Seidi, MY Azarfam, MK Yazdi… - Composites Part B …, 2023 - Elsevier
Biomimetic scaffolds supporting tissue regeneration are complex materials with
multifunctional characteristics. The unique biocompatibility and biodegradability of …

[HTML][HTML] Therapeutic strategies of three-dimensional stem cell spheroids and organoids for tissue repair and regeneration

W Kim, Y Gwon, S Park, H Kim, J Kim - Bioactive Materials, 2023 - Elsevier
Abstract Three-dimensional (3D) stem cell culture systems have attracted considerable
attention as a way to better mimic the complex interactions between individual cells and the …

Responsive hydrogel dressings for intelligent wound management

S Wang, WY Wu, JCC Yeo, XYD Soo, W Thitsartarn… - …, 2023 - Wiley Online Library
Due to global aging problems, the rising number of patients suffering from chronic or hard‐to‐
heal acute wounds imposes a significant burden on healthcare systems. Wound healing is a …

Biomaterials releasing drug responsively to promote wound healing via regulation of pathological microenvironment

H Li, B Li, D Lv, W Li, Y Lu, G Luo - Advanced Drug Delivery Reviews, 2023 - Elsevier
Wound healing is characterized by complex, orchestrated, spatiotemporal dynamic
processes. Recent findings demonstrated suitable local microenvironments were …

Immunomodulatory hydrogels: advanced regenerative tools for diabetic foot ulcer

Y **ong, Q Feng, L Lu, K Zha, T Yu, Z Lin… - Advanced Functional …, 2023 - Wiley Online Library
Diabetic foot ulcer (DFU) is one of the most common complications of diabetes, bringing
physical and mental challenges for patients due to the lack of efficient curative therapy …

Rational design of intelligent and multifunctional dressing to promote acute/chronic wound healing

L Zhou, T Min, X Bian, Y Dong, P Zhang… - ACS Applied Bio …, 2022 - ACS Publications
Currently, the clinic's treatment of acute/chronic wounds is still unsatisfactory due to the lack
of functional and appropriate wound dressings. Intelligent and multifunctional dressings are …

Zwitterionic Polysaccharide‐Based Hydrogel Dressing as a Stem Cell Carrier to Accelerate Burn Wound Healing

Q Yu, H Sun, Z Yue, C Yu, L Jiang… - Advanced …, 2023 - Wiley Online Library
Stem cell therapy integrated with hydrogels has shown promising potential in wound
healing. However, the existing hydrogels usually cannot reach the desired therapeutic …

Mesenchymal stromal cells in hepatic fibrosis/cirrhosis: from pathogenesis to treatment

X Yang, Q Li, W Liu, C Zong, L Wei, Y Shi… - Cellular & Molecular …, 2023 - nature.com
Hepatic fibrosis/cirrhosis is a significant health burden worldwide, resulting in liver failure or
hepatocellular carcinoma (HCC) and accounting for many deaths each year. The …