DNA biosensors and microarrays

A Sassolas, BD Leca-Bouvier, LJ Blum - Chemical reviews, 2008 - ACS Publications
Development of DNA biosensors and DNA microarrays has increased tremendously over
the past few years as demonstrated by the large number of scientific publications in this area …

Taking gene-expression profiling to the clinic: when will molecular signatures become relevant to patient care?

C Sotiriou, MJ Piccart - Nature reviews cancer, 2007 - nature.com
The advent of microarray technology has enabled scientists to simultaneously investigate
the expression of thousands of genes. Gene-expression profiling studies have provided a …

[HTML][HTML] GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland

H Kouros-Mehr, EM Slorach, MD Sternlicht, Z Werb - Cell, 2006 - cell.com
The GATA family of transcription factors plays fundamental roles in cell-fate specification.
However, it is unclear if these genes are necessary for the maintenance of cellular …

Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells

J Lee, JH Mo, K Katakura, I Alkalay, AN Rucker… - Nature cell …, 2006 - nature.com
The mechanisms by which commensal bacteria suppress inflammatory signalling in the gut
are still unclear. Here, we present a cellular mechanism whereby the polarity of intestinal …

Multiple-laboratory comparison of microarray platforms

RA Irizarry, D Warren, F Spencer, IF Kim, S Biswal… - Nature …, 2005 - nature.com
Microarray technology is a powerful tool for measuring RNA expression for thousands of
genes at once. Various studies have been published comparing competing platforms with …

Evaluation of gene expression measurements from commercial microarray platforms

PK Tan, TJ Downey, EL Spitznagel Jr, P Xu… - Nucleic acids …, 2003 - academic.oup.com
Multiple commercial microarrays for measuring genome‐wide gene expression levels are
currently available, including oligonucleotide and cDNA, single‐and two‐channel formats …

GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model

H Kouros-Mehr, SK Bechis, EM Slorach, LE Littlepage… - Cancer cell, 2008 - cell.com
How breast cancers are able to disseminate and metastasize is poorly understood. Using a
hyperplasia transplant system, we show that tumor dissemination and metastasis occur in …

Performance comparison of one-color and two-color platforms within the MicroArray Quality Control (MAQC) project

TA Patterson, EK Lobenhofer… - Nature …, 2006 - nature.com
Microarray-based expression profiling experiments typically use either a one-color or a two-
color design to measure mRNA abundance. The validity of each approach has been amply …

Microarray analysis and tumor classification

J Quackenbush - New England Journal of Medicine, 2006 - Mass Medical Soc
Microarray analysis is a tool that can be used to compare the RNA profile of one cancer with
that of another and to determine the diagnosis and prognosis of cancer. This article provides …

Mammary ductal morphogenesis requires paracrine activation of stromal EGFR via ADAM17-dependent shedding of epithelial amphiregulin

MD Sternlicht, SW Sunnarborg, H Kouros-Mehr, Y Yu… - 2005 - journals.biologists.com
Epithelial-mesenchymal crosstalk is essential for tissue morphogenesis, but incompletely
understood. Postnatal mammary gland development requires epidermal growth factor …